Job description

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Occ Summary

Conduct independent research activities under the guidance of a faculty/mentor inpreparation for a full time academic or research career.

Work Performed

The Neurologic Outcomes Research Group (NORG) at Duke University seeks a talented postdoctoral associate to study the translational systems neuroscience of perioperative neurocognitive disorders (PND) and their relationship to Alzheimer’s disease and related dementias (ADRD). The position is supported by grants from the National Institute of Aging (NIA), the National Heart, Lung and Blood Institute (NHLBI), and the Alzheimer’s Drug Discovery Foundation (ADDF). These grants support a variety of studies by our group on fMRI activity/connectivity changes in PND and ADRD, anesthetic-induced EEG oscillation changes that predict PND and ADRD, and the human neuro-immune response underlying PND and AD. Our group also has one of the world’s largest repositories of pre- and post-operative CSF samples from older surgical patients who also underwent pre- and post-operative cognitive testing and delirium screening, functional neuroimaging and multiple other assessments. Thus, there are significant and unparalleled opportunities for secondary analyses of data already collected by our team on relationships between cognition, pre and post-operative brain connectivity/activity, ADRD CSF biomarkers, pre and intra-operative EEG recordings and other quality of life and mental health assessments.

Additional opportunities exist in advancing perioperative imaging of glial activation, synaptic density, and glymphatics, conducted through the Brain Imaging and Analysis Center (BIAC). The BIAC combines world-class technical facilities, including MRI and electrophysiological research labs, with outstanding faculty drawn from many departments. The Center consists of two research-dedicated human imaging suites, an animal scanner laboratory, a scanner-simulator (mock scanner) facility, a behavioral testing laboratory, a computation and data storage facility, an electronics and RF coil shop, two common image analysis laboratories, and offices for faculty and research staff. Perioperative resources include two 32 channel EEG recording setups, a large -80 freezer repository of perioperative CSF and blood samples, and dedicated office and lab space.

The postdoctoral position is initially for a one-year term but is renewable for additional years, contingent upon strong performance. Programming skills, expertise in MRI and/or EEG analysis, and a PhD in ADRD research, cognitive neuroscience or related fields are prerequisites. Experience with neuropsychological testing is desirable.

Knowledge, Skills and Abilities

See job description for requirements.

Min Degree Requirements: Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.). Should be used for post-doctoral fellows if the candidate has completed all of the require ments for a degree, but the degree has not been formally conferred; the candidate may present evidence of completion of the degree requirements, together with a statement documenting the date on which the degree is t o be conferred.


See job description for education requirements.


See job description for requirements.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.




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Job No:
Posted: 12/1/2020
Application Due: 1/29/2021
Work Type: Full Time