Professional Research Assistant (PRA) or Senior Professional Research Assistant (Sr. PRA)

Job description


University of Colorado – School of Medicine

Professional Research Assistant or Senior Professional Research Assistant


The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.


Seeking Professional Research Assistant or Senior Professional Research Assistant, depending on qualifications. 

Overall Description of Responsibility or Nature of Work

This position reports directly to the Raphael Nemenoff in the Department of Medicine, and is responsible for the study the role of the tumor microenvironment on progression of lung cancer.

Specific Position Duties with Percentages of Time

[ 80 ]% 

[1st area of responsibility]:

The applicant will perform experiments examining factors that mediate progression of lung cancer and response to therapy using mouse models.   These studies will involve using several models of lung cancer progression in mice and analyzing response of lung tumors to immunotherapy and targeted kinase inhibitors.  Experiments will use CT imaging to quantify tumor progression, as well as analysis of tissues from these animals to quantify changes in the tumor microenvironment.  In vitro studies will also examine the interactions between tumor cells and macrophages.  The signaling pathways mediating crosstalk between these cell types will be examined, as well as biological responses, including cell proliferation, differentiation, production of inflammatory cytokines and cell migration/invasion.  These studies will use molecular approaches to overexpress or silence components of signaling pathways in these cells.

[ 20 ]% 

[2nd area of responsibility]:

The applicant will carry out activities related to lab management.  These include purchasing of reagents, maintenance of mouse colonies and fulfilling regulatory requirements (Biosafety, animal protocols).

Salary and Benefits:


Salary is commensurate with skills and experience. The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.


University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.


The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.


Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.



Total Compensation Calculator:


Diversity and Equity:


Please click here for information on disability accommodations:


Office of Equity:


The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

QualificationsMinimum Qualifications:

Bachelor’s degree in biological sciences or related areas. 

To be considered at the Senior PRA level, you would need a master’s degree in biological sciences or related areas, or equivalent experience.


Applicants must meet minimum qualifications at the time of hire.


Preferred Qualifications:

Experience in working with mice is highly desirable.  Experience in analyzing tissues using either flow cytometry or immunostaining would also be important.

Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Nov 20, 2020
Unposting Date: Ongoing




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Job No:
Posted: 12/1/2020
Application Due: 12/13/2020
Work Type: Full Time