GSL Facility Manager (9610C) 12898

San Francisco
Nov 17, 2020
Institution Type
Four-Year Institution

GSL Facility Manager (9610C) 12898 About Berkeley

At the University of California, Berkeley, we are committed to creating a community that fosters equity of experience and opportunity, and ensures that students, faculty, and staff of all backgrounds feel safe, welcome and included. Our culture of openness, freedom and belonging make it a special place for students, faculty and staff.

The University of California, Berkeley, is one of the world's leading institutions of higher education, distinguished by its combination of internationally recognized academic and research excellence; the transformative opportunity it provides to a large and diverse student body; its public mission and commitment to equity and social justice; and its roots in the California experience, animated by such values as innovation, questioning the status quo, and respect for the environment and nature. Since its founding in 1868, Berkeley has fueled a perpetual renaissance, generating unparalleled intellectual, economic and social value in California, the United States and the world.

We are looking for equity-minded applicants who represent the full diversity of California and who demonstrate a sensitivity to and understanding of the diverse academic, socioeconomic, cultural, disability, gender identity, sexual orientation, and ethnic backgrounds present in our community. When you join the team at Berkeley, you can expect to be part of an inclusive, innovative and equity-focused community that approaches higher education as a matter of social justice that requires broad collaboration among faculty, staff, students and community partners. In deciding whether to apply for a position at Berkeley, you are strongly encouraged to consider whether your values align with our Guiding Values and Principles, our Principles of Community, and our Strategic Plan.

Application Review Date

The First Review Date for this job is: November 30, 2020

Departmental Overview

QB3 Genomics at the University of California, Berkeley, is a joint core research facility managed by the California Institute for Quantitative Biosciences (QB3), a cooperative effort between the state of California, private industry, venture capital, and the UC Campuses at Berkeley, San Francisco, and Santa Cruz.

QB3 Genomics is a partnership between the Vincent J. Coates Genomics Sequencing Lab ( GSL - B206 Stanley Hall), the Functional Genomics Laboratory (FGL - 255 LSA) for Library Preparation, and the Computational Genomics Resources Facility (CGRL) for server access and bioinformatics resources. QB3 Genomics offers various library preparation and Next-Generation Sequencing services on Illumina's NovaSeq, HiSeq and MiSeq platforms, the PacBio Sequel II system, as well as array services on an Illumina iScan. QB3 Genomics is also available for custom nucleic acid extraction services for bulk gDNA/RNA or High Molecular Weight gDNA. QB3 Genomics also offers full service Human Genome and Human Exome services in addition to 16s/ITS amplicon microbial community analysis services.

QB3 Genomics' mission is to make genomics processing affordable to UC Berkeley and the greater genomics community.


  • Operate, maintain, troubleshoot 2 Illumina HiSeq 4000s, 1 HiSeq 2500 v2, 2 Illumina MiSeqs, 1 Pacific Biosciences Sequel, and accessory robotics equipment and thermal cyclers to perform appropriate QC on sequencing libraries.
  • Supervise sample submission and movement through workflows
  • Supervise sample tracking from submission through storage in barcodes storage tubes and record eventual disposal of samples
  • Inspect and approve every single sequencing library submitted to the core
  • Dictate the exact sequencing parameters for every sequencing run performed in the core and supervise execution of operations
  • Manage the flow of samples prepared by the FGL in transition to the VCGSL
  • Supervise all VCGSL core staff and students and hold responsibility for all of their actions
  • Ensure data return to users in a timely fashion post sequencing (Director will supervise actual data processing)

  • Work with the Director to develop and implement single-molecule sequencing sample extraction protocols for high molecular weight DNA
  • Work with the Directory to develop protocols to generate PacBio single molecule sequencing libraries
  • Work with the Director to develop protocols to efficiently use the PacBio Sequel with minimal reagent waste.
  • They will hire and train a new SRAII to take over all PacBio operations once instructed by Director.
  • Provide support for all workflows between GSL and FGL

Required Qualifications
  • B.A or B.S. in a science discipline and/or equivalent years experience/training and/or 5+ years working in life sciences or a biological research facility
  • The successful candidate will be cooperative, team-oriented, pay strict attention to detail, keep industry-standard records and have good communication skills
  • Minimum 2 years experience operating HiSeqs and MiSeqs
  • Minimim 2 years experience preparing and troubleshooting Illumina gDNA and RNAseq libraries
  • Minimim 2 years experience running qualitative and quantitative library QC assays
  • Experience preparing Pacific Biosciences SMRT libraries
  • Admininstrative level skills operating and programing in Clarity LIMS
  • Expert abilities to provide help to users with custom Illumina sequencing adapter design and the ability to check adapter compatibility with different Illumina platforms and chemistry versions

  • Covaris
  • Apollo 324
  • Megaruptor
  • Pippin Prep, Blue Pippin, Sage-ELF, Pippin Pulse
  • Fragment Analyzer (gDNA and RNA assays)
  • Bioanalyzer (gDNA and RNA assays)
  • Any quantitative PCR instrument
  • epMotion Liquid handler
  • cBot clustering for HiSeq 2500 and 4000
  • Hiseq4000, HiSeq2500 v2, MiSeq

Preferred Qualifications
  • Track record of written and verbal communication skills as judged by publications and oral presentations
  • Perfunctory Linux/Unix command line skills with some knowledge of Perl or Python
  • Experience with Bcl2fastq 2.18 with UMI parsing abilities
  • DNA extraction experience from various organisms

Salary & Benefits

Salary is commensurate with experience. Hiring range is up to $89,991/annually.

For information on the comprehensive benefits package offered by the University visit:

How to Apply

Please submit your cover letter and resume as a single attachment when applying.

Other Information

This is a full-time career/exempt position which is governed by the terms and conditions in the agreement for the Research Support Professionals Unit (RX) between the University of California and the University Professional and Technical Employees (UPTE). The current bargaining agreement manual can be found at:

Conviction History Background

This is a designated position requiring fingerprinting and a background check due to the nature of the job responsibilities. Berkeley does hire people with conviction histories and reviews information received in the context of the job responsibilities. The University reserves the right to make employment contingent upon successful completion of the background check.

Equal Employment Opportunity

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. For more information about your rights as an applicant see:
For the complete University of California nondiscrimination and affirmative action policy see:

To apply, visit

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