Research Assistant 2

Job description

Job Title: Research Assistant 2
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8573
Job Description Position Objective

Working under general supervision, the Research Assistant 2 will plan, facilitate and carry out ongoing diagnostic and research work for a lab dedicated to work on prion and prion-like diseases (Alzheimer’s disease). This involves selection and characterization of antibodies and ligands, transgenic mice breeding and genotyping, and preparation of cells and media for cultures and western blot techniques. The research assistant will be responsible for managing laboratory inventory and quality control. The research assistant will exercise tact and independent judgment in difficult and important transactions concerning other institutions and the university.

Essential Functions

    Plan and carry out research assignments including the ELISA -formated diagnostic tests such as Conformation Dependent Immunoassay (CDI) and conformational stability assay (CSA). Handle potential emergencies related to the laboratory operations in accordance with Environmental Health and Safety (EHS) protocols and training. (36%)Plan and crarry transgenic mice breeding and genotyping, preparation of explant neurons and media for cell cultures, and maintenance of neuron cultures. (30%) Plan, prepare and conduct human tissue processing in Biosafety Level II using tissue homogenizers and liquid handling systems. (6%) Collect and analyze data from experiment results. May assist with the development of new ultra-sensitive immunochemical detection methods in different tissues. (6%)Participate in organizing and maintaining certain equipment facilities. Oversee and track orders and inventory. Maintain stocks and solutions. (10%)Process monthly ELISA quality control checks with lab director. (6%)Train new laboratory technicians and student employees as necessary. (6%)

NonEssential Functions

Perform other duties as assigned.


Department: Reports directly to the manager and director of the center. Frequent contact with other members of the research and diagnostic groups, student employees, and other support personnel, in addition to faculty and postdoctoral fellows.

University: Occasional contact with faculty and staff in the School of Medicine, University Hospital Department of Medicine and numerous support and service departments in University Hospitals and Case Western Reserve University.

External: Occasional contact with suppliers of laboratory products and supplies.

Students: Frequent contact with student employees.

Supervisory Responsibility

This position has no direct supervision of staff employees. Train new staff; direct the work of students.


Education and Experience: Bachelor's degree and 1 to 3 years of related experience or Associate's degree in an approved biotechnology program and 2 to 4 years of experience.


    Knowledge and understanding of commonly-used concepts, practices, and procedures in the prion -like field. Ability to perform Western blotting, ELISA and Gel electrophoresis 1-D and 2-D and operate standard lab equipment. Effective oral and written communication skills, and good interpersonal skills; must demonstrate the ability to effectively and professional communicate and work with various individuals from a broad spectrum of disciplines, technical and educational backgrounds within the department, school and university, and with individuals outside the university.Strong organization skills; ability to multi-task, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy, time management skills, and follow-through. Ability to work effectively independently and collaboratively within a team. Must be highly motivated, responsible, dependable and a self-starter. Ability to work with sensitive information and maintain confidentiality.Ability to maintain familiarity and demonstrate knowledge of the NPDPSC priorities, leadership and programs.Effective problem-solving skills; must demonstrate excellent analytical skills, sound judgment and good decision-making.Must demonstrate flexibility and ability to work under pressure; must be able and willing to work in a fast-paced, changing environment, and conform to shifting priorities, demands and timelines.Willingness and ability to relay on and follow instructions and pre-established guidelines to perform the functions of the job.Ability to operate laboratory equipment including but not limited to a centrifuge, shaker, cryostat, and microtome.Familiarity with policies and procedures of NPDPSC, Pathology Department, School of Medicine and Case Western Reserve University. Proficiency in Microsoft Office and database management. Must demonstrate willingness to learn new techniques, procedures, processes, and computer programs as needed. Ability to meet consistent attendance.Ability to interact with colleagues, supervisors and customers face to face.

Working Conditions

Standard laboratory conditions with some hazardous chemicals. Special hazards include biohazardous (potentially infectious) human brain and cerebrospinal fluid. The following personal protective equipment required: appropriate gloves, protective eyewear, laboratory coat, and safety shoes.

Diversity Statement

In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Reasonable Accommodations

Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.





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Job No:
Posted: 11/15/2020
Application Due: 2/13/2021
Work Type: