Research Assistant 3
Job Title: Research Assistant 3
Location: Case Main Campus
Full/Part Time: Full-Time
Job ID: 8550
Job Description POSITION OBJECTIVE
- Working closely with the principal investigator, carry out complex research assignments of a non-routine nature aimed to identify and characterize functional interactions between HIV and cellular proteins. (35%)Coordinate research activities; design, construct and produce retro- and lentiviral vectors using innovative cloning techniques for their use in complex molecular/biochemical experiments aimed to identify and characterize novel interactions between viral and cellular proteins, and for gene transfer into a broad range of indicator cell lines. Experiments will be performed in both established and primary human cells under BL2 and BL2+ containment conditions. (35%).Devise new protocols and techniques and utilize newly developed research techniques, as appropriate. Evaluate adequacy of techniques and protocols for non-routine biochemical experiments including, but not limited to, those designed to purify complexes between viral and cellular proteins for their subsequent proteomic analyses. Perform downstream characterization of high priority proteomic hits and other relevant targets using appropriate biochemical methods. May co-author research projects. May supervise students and technicians. (15%)Maintain accurate and thorough records of the obtained research data. May monitor the laboratory budget. (10%).
- Practical knowledge and understanding of commonly used concepts, practices and procedures within the biochemistry, molecular-genetics and/or virology fields. Must possess the following basic technical skills: sterile technique; reagent and media preparation, cell culture, DNA transfection, preparation of plasmid DNA, molecular cloning, immunoprecipitation, western blotting, PCR, biochemical purification techniques and/or production of retroviral/lentiviral vectors.Must be highly motivated, conscientious and willing to learn.Professional and effective verbal and written communication skills. Strong organization skills; ability to multi-task, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy, time management skills and follow-through. Ability to work effectively independently and collaboratively within a team. Ability to problem-solve effectively and assist in the development and implementation of alternative solutions as needed. Must demonstrate good judgment and logical decision-making.Must be compliant with applicable regulatory guidelines.Ability to operate complex laboratory equipment including, flow cytometer and QPCR.Familiarity with standard laboratory safety policies and procedures.Proficiency in Microsoft Office. Must demonstrate willingness and ability to learn new techniques, procedures, processes and computer programs as needed.Ability to meet consistent attendance. Ability to interact with colleagues, supervisors and customers face to face.
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.