PharmacologyDepartment Website Link:
UAHS - TucsonAddress:
University of Arizona Health Sciences, Tucson, AZ USAPosition Highlights:
A Researcher/Scientist III position is currently available in the Translational Pain Neuroscience laboratory at the University of Arizona in Tucson in the Dr. Frank Porreca and Dr. Edita Navratilova lab to undertake cutting-edge research in pain drug discovery. The research is focused on investigating drug targets in neural circuits underlying affective, emotional and cognitive pain behaviors in a variety of rodent pain models including migraine, post-traumatic headache neuropathic pain and others. The laboratory uses novel viral and fluorescent neuronal tracing methods in combination with genetic mouse models, fast scan cyclic voltammetry, optogenetic and chemogenetic techniques and CRISPR gene editing to investigate the structural connectivity and function of neural networks processing pain.
Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state and optional retirement plans; access to UA recreation and cultural activities; and more!The University of Arizona has been recognized for our innovative work‐life programs. For more information about working at the University of Arizona and relocations services, please click here.
As a cost-saving measure related to the impact of COVID-19, Furlough and Furlough-Based Salary Programs have been approved by the Arizona Board of Regents. All new hires subject to the programs will be notified in accordance with adopted Furlough and Furlough-Based Salary Programs guidelines and will be required to comply with all measures. To learn more about the programs and whether this position is affected, please visit hr.arizona.edu/FY-2020-2021-Furlough-Program.Duties & Responsibilities:
The goal of these studies is to identify new neural mechanisms and potential targets for chronic pain.
Additional interest of the laboratory is on characterization of cellular adaptations within the dorsal root and trigeminal nociceptors occurring in chronic pain conditions using in vitro neuronal cellular assay. We are seeking an outstanding, highly motivated applicant to join our vibrant research team. Our group is well funded by several NIH grants. The PIs value creativity, dedication, and teamwork. The applicant will be engaged in group lab meetings, departmental seminars and encouraged to present their work at national and international scientific conferences and publish manuscript in high quality journals. The successful applicant should be able to optimize and develop assays such as in vitro calcium imaging, fluorescence energy transfer assays, and neurotransmitter ELISA immunoassays. Background in pain research and rodent handling is desired but not required.The applicant should have experience with tissue cell culture, in vitro cellular assays for drug discovery including chromogenic, fluorescent and luminescent assays, western blotting and fluorescent microscopy.
- Independentlyexplore mechanisms of pain chronicity. Study anatomy of brainstem modulatorysites.
- mediating and maintaining chronic pain using genetically modified animals andviral tracing technology.
- Performsterile surgeries on small animals to induce a variety of chronic pain statesand allow for different routes of drug delivery; design new surgical procedures and developnew protocols to meet the needs of new research projects, perform necropsy and tissue collections toobtain specific areas of the brain/ spinal cord, or peripheral organs.
- Performdiffering routes of administration such as i.p., i.v., i.m., s.c., etc. insmall animals; perform behavioral testing on rodents as well as data analysis.
- Analyzepublished literature and prepare data for publication in national andinternational peer-reviewed journals.
- Supervisegraduate and undergraduate students.
- Bachelor'sdegree or equivalent advanced learning attained through professional levelexperience required.
- Minimumof 5 years of relevant work experience required
• Ph.D. in Earth and Planetary Science, Materials Science, Chemistry, Physics or related field with strong electron microscopy background • Minimum of 2 years of laboratory-management experience • Minimum 2 years of experience in operation of SEM system(s) preferably including high resolution SEM, variable pressure SEM, EDS, EBSD, and Raman spectroscopy techniques • Experience with electron backscatter diffraction and in situ Raman analysis • Experience with TEM a plus, including scanning TEM (STEM), energy-dispersive X-ray spectroscopy (EDS), and electron energy-loss spectroscopy (EELS) of planetary materials • Familiarity with proper and ethical imaging practices and protocols • Fundamental knowledge on the operating characteristics of electron microscopes, vacuum systems, and data storage • Excellent oral/written communication and superior organization skills • Ability to work independently and as part of a teamFLSA:
ExemptFull Time/Part Time:
Full TimeNumber of Hours Worked per Week:
Yes - Full BenefitsRate of Pay:
salary at 1.0 full-time equivalency (FTE)Grade:
8Career Stream and Level:
Researchers & ScientistsJob Function:
ResearchType of criminal background check required::
Name-based criminal background check (non-security sensitive)Number of Vacancies:
1Target Hire Date:
Expected End Date:
Contact Information for Candidates:
11/12/2020Open Until Filled:
YesDocuments Needed to Apply:
Curriculum Vitae (CV) and Cover LetterSpecial Instructions to Applicant:
At the University of Arizona, we value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community. As an Hispanic-serving institution, we translate these values into action by seeking individuals who have experience and expertise working with diverse students, colleagues, and constituencies. Because we seek a workforce with a wide range of perspectives and experiences, we provide equal employment opportunities to applicants and employees without regard to race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity, or genetic information. As an Employer of National Service, we also welcome alumni of AmeriCorps, Peace Corps, and other national service programs and others who will help us advance our Inclusive Excellence initiative aimed at creating a university that values student, staff and faculty engagement in addressing issues of diversity and inclusiveness.