Researcher/Scientist IV (Pharmacology and Toxicology)

Tucson, AZ
Nov 13, 2020
Institution Type
Four-Year Institution
Posting Number:



Pharmacology and Toxicology

Department Website Link:


UAHS - Tucson


1703 E. Mabel , Tucson, AZ 85721-0207 USA

Position Highlights:

This position is for a synthetic medicinal chemist who will act as a leading member of a medical chemistry team focused on small molecular drug discovery. The position requires proven experience in synthetic medicinal chemistry, including design and synthesis of small molecules with drug-like characteristics, including extensive knowledge and use of CAMD. The position will be supported in part by Alzheimer's drug discovery R01 and R21 grants. The applicant will be expected to grow into a leadership role with the probability of direct reports in the Hulme and Thatcher groups and will be encouraged to write grants as co-I and MPI.

Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state and optional retirement plans; access to UA recreation and cultural activities; and more!

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As a cost-saving measure related to the impact of COVID-19, Furlough and Furlough-Based Salary Programs have been approved by the Arizona Board of Regents. All new hires subject to the programs will be notified in accordance with adopted Furlough and Furlough-Based Salary Programs guidelines and will be required to comply with all measures. To learn more about the programs and whether this position is affected, please visit

Duties & Responsibilities:

  • Planning and execution of synthesis of small molecule synthons, hits, lead compounds, and development candidates.
  • Design of ligands and inhibitors for drug targets. Purification and full characterization of small molecules along the drug discovery and development pipeline.
  • Gram-scale synthesis and purification of development candidates for in vivo studies. Use of CAMD and relevant in silico methods of drug design and discovery.
  • Trouble-shooting and optimizing synthetic methodology.
  • Mentoring of junior trainees. Writing papers and patent applications.

Minimum Qualifications:

  • Bachelor's degree or equivalent advanced learning attained through professional level experience required; OR a PhD or equivalent terminal degree in a related discipline.
  • Minimum of 8 years of relevant work experience required.

Preferred Qualifications:

-At least 8 years experience in drug discovery beyond a PhD in synthetic organic or medical chemistry. -Synthesis, chromatography, characterization, cutting-edge CAMD, purification scale-up



Full Time/Part Time:

Full Time

Number of Hours Worked per Week:


Job FTE:


Work Calendar:


Job Category:


Benefits Eligible:

Yes - Full Benefits

Rate of Pay:

$59,828 - $86,417

Compensation Type:

salary at 1.0 full-time equivalency (FTE)



Career Stream and Level:


Job Family:

Researchers & Scientists

Job Function:


Type of criminal background check required::

Name-based criminal background check (non-security sensitive)

Number of Vacancies:


Target Hire Date:


Expected End Date:

Contact Information for Candidates:

Gregory Thatcher - [email protected]

Christopher Hulme - [email protected]

Open Date:


Open Until Filled:


Documents Needed to Apply:

Curriculum Vitae (CV) and Cover Letter

Special Instructions to Applicant:

Diversity Statement:

At the University of Arizona, we value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community. As an Hispanic-serving institution, we translate these values into action by seeking individuals who have experience and expertise working with diverse students, colleagues, and constituencies. Because we seek a workforce with a wide range of perspectives and experiences, we provide equal employment opportunities to applicants and employees without regard to race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity, or genetic information. As an Employer of National Service, we also welcome alumni of AmeriCorps, Peace Corps, and other national service programs and others who will help us advance our Inclusive Excellence initiative aimed at creating a university that values student, staff and faculty engagement in addressing issues of diversity and inclusiveness.

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