Post-Doctoral Fellow
Job description
DescriptionUniversity of Colorado – School of MedicinePost- Doctoral Fellow
The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.
The Department of Obstetrics and Gynecology has full time openings for Postdoctoral Fellows in the Division of Reproductive Sciences (Jansson/Powell group). The post docs will be working in the area placental origins of disease, studying the cellular and molecular mechanisms of regulation of placental function and to investigate the role of placental function in determining fetal growth and long-term health. Specifically, the post-doctoral fellows will perform mechanistic studies in (1) human placental experimental models, (2) novel cutting-edge mouse models employing Piggy Bac transposon mediated transgenesis and lentivirus-mediated blastocyst transfection, respectively, to achieve trophoblast-specific gene targeting and (3) determining the role of placental exosomes in regulating maternal glucose tolerance and in the initiation of parturition. The research group employs physiological, molecular and translational approaches. The lab utilizes a wide variety of model systems including primary human trophoblast cells and explants, human placental tissue, mice, rats, and non-human primates.Nature of the work:The Department of Obstetrics and Gynecology has full time openings for two Postdoctoral Fellows in the Division of Reproductive Sciences (Jansson/Powell group). The two post docs will be working in the area placental origins of disease, studying the cellular and molecular mechanisms of regulation of placental function and to investigate the role of placental function in determining fetal growth and long-term health. Specifically, the two post-doctoral fellows will perform mechanistic studies in (1) human placental experimental models, (2) novel cutting-edge mouse models employing Piggy Bac transposon mediated transgenesis and lentivirus-mediated blastocyst transfection, respectively, to achieve trophoblast-specific gene targeting and (3) determining the role of placental exosomes in regulating maternal glucose tolerance and in the initiation of parturition. The research group employs physiological, molecular and translational approaches. The lab utilizes a wide variety of model systems including primary human trophoblast cells and explants, human placental tissue, mice, rats, and non-human primates. Current projects include studies of the impact of lipids on placental function, identifying mechanistic links between altered placental function, fetal growth and adult health, placental-fetal signaling in modulating fetal organ development, the role of placental exosomes in the development of pregnancy complications and exploring the potential of proteins and miRNA secreted by the placenta as novel interventions in prematurity. Supervision received:A principal investigator (Dr. Thomas Jansson) with an established laboratory on the Anschutz Medical Campus will supervise this position. Supervision Exercised:None Examples of work performed:- Perform experiments using advanced biomedical research techniques and develop new methods/applications.Have the primary responsibility for writing scientific publications. Present the results at national and international scientific meetings.Write and submit grant applications to major funding agenciesProvide instructions to students, research associates and other post-doctoral fellows.
QualificationsMinimum Qualifications
- A minimum of a PhD in relevant scientific area such as Physiology, Molecular Biology and Cell BiologyA working knowledge of computer software for data analysis and presentation.
- Background in perinatal biology
Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Nov 6, 2020
Unposting Date: Ongoing