DescriptionUniversity of Colorado Denver l Anschutz Medical CampusDepartment of Biochemistry and Molecular GeneticsPost-Doctoral FellowPosition 00779107 – Requisition 19349 The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds. The University of Colorado Denver | Anschutz Medical Campus is a comprehensive urban research university serving more than 28,000 students in metropolitan Denver and online. We award nearly 4,000 degrees each year, including more graduate and professional degrees than any other Colorado public institution. With our solid academic reputation, award-winning faculty and renowned researchers, we offer 119 highly rated degree programs through 13 schools and colleges. The University of Colorado Denver | Anschutz Medical Campus is well known for its distinctive and highly productive research programs, its world-class health facilities at the Anschutz Medical Campus and its well-established partnerships in business, industry and government. These campuses currently have over $400 million in research awards each year. In addition to the wide array of health-related programs and facilities offered at our Anschutz Medical Campus, a significant number of undergraduate and graduate degree programs are taught at our comprehensive campus in the heart of downtown Denver. Denver is one of America’s most vibrant urban centers and the downtown campus, located just steps from the Denver Center for Performing Arts and the LoDo District, affords our students, faculty and staff access to a broad array of academic, professional, community, recreational and cultural outlets. Postdoctoral FellowSingle-cell technology development in the Hesselberth Lab  The laboratory of Jay Hesselberth seeks a Postdoctoral Fellow to develop new single-cell technologies. Our lab is in the Department of Biochemistry and Molecular Genetics and part of the newly formed RNA Bioscience Initiative at the University of Colorado School of Medicine.    We recently developed two new approaches to measure biochemical activities in single cells and to enable molecular tracking of molecules in vivo. These approaches lay the groundwork for new methods and applications.   The Hesselberth lab recently developed two new single-cell approaches to measure biochemical activities in single cells (https://pubmed.ncbi.nlm.nih.gov/32286626/) and to track DNA conjugates through tissues (https://www.biorxiv.org/content/10.1101/2020.08.19.219527v1). We now plan to deploy these methods broadly and also develop companion technologies.   A Postdoctoral Fellow will focus on their development and application and will focus on the following projects:

• Developing of new single-cell biochemical methods to enable CRISPR and small molecule inhibitor screens
• Integrating single cell biochemistry data with single cell RNA-seqg
• Optimizing molecular tracking devices for studying ligand dissemination in tissue
• Applying these tools to spatial approaches to understand biochemical activities and ligand dissemination in situ. 

The candidate will also work closely with computational biologists in the RNA Bioscience Initiative to develop new analysis strategies for single cell biochemistry and molecular tracking data. Salary and Benefits:

Salary is commensurate with skills and experience. The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Benefits: https://www.cu.edu/employee-services/benefits.

Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation

Diversity and Equity:

Please click here for information on disability accommodations: http://www.ucdenver.edu/about/departments/HR/jobs/Pages/JobsatCUDenver.aspx 

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

QualificationsMinimum Qualifications:

• PhD in molecular biology or related discipline 
• Working knowledge of single-cell mRNA sequencing, molecular biology and high throughput DNA sequencing data analysis

Preferred Qualifications:

• Experience in single-cell biology
• Expertise in R, Python, and next generation sequencing analysis

Applicants must meet minimum qualifications at the time of hire. 

Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Oct 19, 2020
Unposting Date: Ongoing