Research Scientist
- Employer
- University of Pennsylvania
- Location
- Biomedical Research Building 2 - 9th Floor
View more
- Administrative Jobs
- Academic Affairs, Research Staff & Technicians
- Institution Type
- Four-Year Institution
Job Details
Job location: Biomedical Research Building 2 - 9th Floor
Employment Type: Full-time
Posted data: 2020-10-15
Req: JR00025430
University OverviewThe University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.Posted Job TitleResearch ScientistJob Profile TitleResearch Specialist DJob Description SummaryThe Wangensteen Laboratory is using cutting-edge molecular biology techniques in mouse models to address major knowledge deficits in liver disease mechanisms. We are looking for a highly experienced and motivated scientist with an interest in molecular oncology, immunotherapy, CRISPR/Cas9, high throughput techniques, and in vivo modeling. We aim to recruit a highly ambitious scientist to lead a funded project to discover new therapeutic targets for liver disease and cancer. The ideal candidate will have a PhD or MD with post-doctoral experience and will have a successful background in genomics, signaling, and/or mouse modeling of disease. The project will involve genetic screens using CRISPR/Cas9 technology using methods we have developed in lab, which is leading to a number of impactful publications. This position is suited for an accomplished scientist who is eager to make new discoveries in liver cancer. The goal is to make a real impact on liver disease.Job Description
We are seeking a PhD Research Scientist who will initiate and manage the development of multiple funded projects at the direction of the Principal Investigator.
The main research pipeline involves design and building of gRNA plasmid libraries for CRISPR screening, injection of these into mice for genetic screening, tissue harvesting and building libraries for high throughput sequencing, bioinformatic analysis of the sequencing results, mechanistic studies to work-up leads from the screens, extensive quality control, careful review of relevant scientific literature, and written and verbal communication of the results.
We are seeking an ambitious, curious, hard-working scientist who enjoys discovery at the bench and who can utilize basic bioinformatic techniques to confirm and extend results.
The P.I. Dr. Kirk J. Wangensteen is a physician-scientist who is specialized in Gastroenterology and Hepatology, and who has been at Penn for more than 9 years. The lab is situated in a highly modern facility, with natural light and easy access to equipment, reagents and cores. The environment is collegial, friendly, and open-minded; we like to explore all great scientific ideas. In addition, Penn has outstanding seminar series and provides numerous career development opportunities.
Position contingent upon funding
Qualifications
Required - At least Masters Degree and 3-5 years of related experience in research, project and people management or equivalent combination of education and experience.
Preferred - PhD with 3-5 years of related experience in research, project and people management or equivalent combination of education and experience.
Working Conditions
Office, Library, Computer Room; Requires extensive safety
Physical Effort
Typically sitting at a desk or table; Occasional lifting 25 lb. or less
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Organization
Welcome to the University of Pennsylvania! Penn is the largest private employer in Philadelphia and is a world-renowned leader in education, research, and innovation.
Across our 12 highly-regarded schools, more than 25,000 students, and more than 4,000 faculty members, we become one university: a wide-ranging, ever-changing community that draws its strength from a multitude of races, ethnicities, genders, sexual orientations, historical traditions, ages, religions, disabilities, veteran status, interests, perspectives, and socioeconomic backgrounds.
Penn carries on the principles and spirit of its founder, Benjamin Franklin: entrepreneurship, innovation, invention, outreach, and a pragmatic love of knowledge. Franklin's practical outlook has remained a driving force in the university's development. To learn more, visit About Penn.
Vision
As engines of knowledge and new ideas, universities have the unique potential to define the future rather than be defined by it; to pioneer change rather than merely manage it. To do so requires a plan both visionary and pragmatic. The Penn Compact 2022 motivates community members to innovate, be radically inclusive, and positively impact their local, national, and global communities.
Penn’s fundamental priorities — increasing access, integrating knowledge and engaging locally, nationally and globally — are supported by the three core values that make us uniquely Penn: inclusion, innovation, and impact.
Learn about the signature initiatives of the Penn Compact 2022:
- Global Connections President’s Engagement Prizes President's Innovation Prize Penn Integrates Knowledge University Professors
Diversity
Understanding and appreciating diversity is one of Penn's most important priorities and is fundamental to success in today's world.
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
To learn more about Diversity and Inclusion at Penn visit:
- Diversity at Penn Resources Supporting Diversity Penn Diversity Facts and Figures Penn's Diversity Timeline 1740-1997
Benefits
Penn offers a wide range of benefits and perks - from Penn's retirement Matching Plan to bike repair stations to access to the full LinkedIn Learning library to adoption assistance to workshops at the letterpress and book arts studio and much more!
- Penn HR Benefits Be in the Know Wellness Campaign Penn Home Ownership Services Campus Shuttles & Buses Resources for Cyclists Deals@Penn Common Press
Campus and Beyond
We invite you to explore our campus and its stately buildings and state-of-the-art facilities.
- Penn Park Morris Arboretum Penn Campus Arboretum: 6,800 Campus Trees Penn Recreation Penn Libraries Shop Penn
Try our self-guided tour! Come and visit!
Learn about sustainability at Penn.
News
Stay up-to-date with Penn's response to COVID-19: Coronavirus Information & Resources.
Penn supports news publications that tell the ongoing story of the University community, communications services for external media, telephone and video services, and other media resources: Campus Media
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- Telephone
- (215) 898-7372
- Location
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3451 Walnut Street
Philadelphia
PA
19104
US
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