Job location: Stellar-Chance-F5

Employment Type: Full-time
Posted data: 2020-10-06
Req: JR00025352
University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title

Research Specialist D (Pathology and Lab Medicine Dept.)

Job Profile Title

Research Specialist D

Job Description Summary

A position is available for a motivated and detail-oriented team-player. The Melenhorst laboratory is a newly established research group in the Department of Pathology and Laboratory Medicine of the University of Pennsylvania. By studying T cell biology in cancer patients and the tumor microenvironment in chronic lymphocytic leukemia and other malignancies we aim to understand and improve the anti-tumor efficacy of adoptively transferred gene-modified T cells. The laboratory has identified mechanisms of response to CAR T cell therapy in chronic lymphocytic leukemia and developed an ex vivo model system to identify the most potent precursor cells of CAR T cells. We are hiring a highly motivated research specialist D with a strong background in translational immunology. The candidate will take the lead role in a project with a start-up biotechnology company (IASO Biotherapeutics) to develop a precision cell engineering platform for the generation of chimeric antigen receptor-redirected T cell therapies for blood cancer. In addition, the individual will be working on biomarker discovery, including data analysis and design of the functional validation strategy and the design and execution of the large-scale manufacturing process.

Job Description

A position is available for a motivated and detail-oriented team-player. The Melenhorst laboratory is a newly established research group in the Department of Pathology and Laboratory Medicine of the University of Pennsylvania. By studying T cell biology in cancer patients and the tumor microenvironment in chronic lymphocytic leukemia and other malignancies we aim to understand and improve the anti-tumor efficacy of adoptively transferred gene-modified T cells. The laboratory has identified mechanisms of response to CAR T cell therapy in chronic lymphocytic leukemia and developed an ex vivo model system to identify the most potent precursor cells of CAR T cells. We are hiring a highly motivated research specialist D with a strong background in translational immunology. The candidate will take the lead role in a project with a start-up biotechnology company (IASO Biotherapeutics) to develop a precision cell engineering platform for the generation of chimeric antigen receptor-redirected T cell therapies for blood cancer. In addition, the individual will be working on biomarker discovery, including data analysis and design of the functional validation strategy and the design and execution of the large-scale manufacturing process.

This position is contingent upon funding.

Qualifications

Masters and 3-5 years of experience and demonstrated experience in academic cellular immunology research or equivalent combination of experience and education. PhD in immunology strongly preferred. A broad knowledge base of immunology including the biology of human T cells is required. Demonstrated abilities to multi-task and exhibiting effective time management skills are required. Prior laboratory experience including mammalian tissue culture is required. Specialized training on utilizing multi-color flow cytometric instruments and data analysis using Flow Jo software are preferred. Hands-on experience with quantitative PCR platforms preferred. Candidate must exhibit excellent computer skills, including expertise in Microsoft Office applications. Preference will be given to candidates who indicate a strong desire to build a career in the translational sciences field.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$50,684.00 - $91,232.00

Affirmative Action Statement 
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements 
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.