Research Assistant 2
Job Title: Research Assistant 2
Location: Case Main Campus
Full/Part Time: Full-Time
Job ID: 8458
Working under general supervision, plan and carry out project in accordance with general plans. The research project is to manage and perform daily operations for the Case Comprehensive Cancer Center Radiation Resources Shared Resource. Responsibilities will include coordination of clinical research activities for researchers, clinical faculty, fellows, and multidisciplinary clinical teams; to aid researchers with design and implementation of interventions, data collection, data analysis, data presentation and manuscript preparation. This position also performs biomedical research to characterize processes involved in response of cancer cells to novel cancer chemotherapy treatments and organize and maintain laboratory facilities. This position will work with animals.
- Conduct a series of experiments to supply scientific information as part of a larger project. Safely work with radiation and radioactive materials in support of a large portfolio of cancer research projects. Maintain and operate ionizing radiation-producing devices for cancer researchers, operating equipment for which access is tightly controlled by federal regulation. Consult with users concerning instrumentation, services, training requirements, and security clearances. (30%)
- Work with preclinical (animal) and cell system models, offering focal radiation delivery to small animals with Radiation Oncology clinical devices. Plan and carry out laboratory projects requiring knowledge of sterile technique, cell culture and molecular biology protocols. Performs biomedical research to characterize processes involved in response of cancer cells to novel cancer chemotherapy treatments. (20%)
- Assist existing users. Train and credential new users. Train new users in the proper and safe operation of the equipment. Technical assistance upon request for dose and dose-rate calculations, hands-on assistance with experiments, design of specialized shields, and other problem solving such as design experiments so that they are compliant with Radiation Safety rules and regulations. (20%)
- Research and identify, in conjunction with the principal investigator, the identification of new services that would benefit users and work towards securing the associated equipment. (10%)
- May assist in developing improved techniques, projection methods or procedures to characterize processes involved in response of cancer cells to novel cancer chemotherapy treatments. May assist in developing improved techniques, projection methods or procedures to characterize processes involved in response of cancer cells to novel cancer chemotherapy treatments including clonogenic assays and detection of DNA damage by gamma-H2X western blots and comet assays. (10%)
- Collect and analyze experimental data outputs from readers and detectors. Research Assistant will be using Excel, MATLAB, or other software to calculate means and standard deviations for ongoing experiments. (5%)
- Oversee inventory of radiation equipment and supplies. Ensure there are enough supplies on hand to conduct experiments. Assist users with scheduling equipment and track use for data reporting purposes. (5%)
- Perform other duties as assigned. (<1%)
Department: Daily contact with research assistants, research associates while maintaining and operating ionizing radiation-producing devices for cancer researchers.
University: Routine contact with core’s users from across CWRU while maintaining and operating ionizing radiation-producing devices for cancer researchers. Contact with procurement officials for ordering supplies.
External: Routine contact with core’s users from CWRU affiliate research partners while maintaining and operating ionizing radiation-producing devices for cancer researchers. Periodic contact for shipping and receiving supplies from other labs/companies related to maintaining and operating ionizing radiation-producing devices for cancer researchers.
Students: Daily interactions with graduate students and post-docs while maintaining and operating ionizing radiation-producing devices for cancer researchers.
Train new staff; direct the work of students.
Education and Experience: Bachelor's degree (preferably in Biology or Chemistry) and 1 to 3 years of related experience or Associate's degree in an approved biotechnology program and 2 to 4 years of experience.
- Ability to safely work with radioactivity and radiation, chemicals, and lab animals.
- Ability to meet and maintain training and credentialing requirements for access to the core’s resources and performance of its services.
- Ability to perform general biomedical laboratory techniques including small animal handling, sterile technique, basic cell culture and basic molecular biology protocols.
- Ability to perform laboratory techniques analyzing DNA/RNA, protein, and tissues using a variety of techniques including Western blots, RCR, tissue sectioning, and animal surgery.
- Excellent oral and written communication skills and interpersonal skills; must demonstrate the ability to effectively and professionally communicate and work with various individuals from a broad spectrum of disciplines, technical and educational backgrounds within the department, school and University, and with individuals outside the university. Ability to interact with colleagues, supervisors and customers face to face.
- Ability to meet consistent attendance.
- Strong organization skills; ability to multi-task, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy, time management skills, and follow-through.
- Ability to work effectively independently and collaboratively within a team. Must be highly motivated, responsible, dependable and a self-starter.
- Effective problem-solving skills; must demonstrate excellent analytical skills, sound judgment and good decision-making.
- Must demonstrate flexibility and ability to work under pressure; must be able and willing to work in a fast-paced, changing environment, and conform to shifting priorities, demands and timeline.
- Willingness and ability to rely on and follow instructions and pre-established guidelines to perform the functions of the job.
- Proficiency in Microsoft Office.
- Must demonstrate willingness to learn new techniques, procedures, processes, and computer programs as needed.
- Must demonstrate compliance with university animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.
- Must demonstrate compassion for animals within university facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.
General laboratory working environment. Employee will be exposed to radiation/radioactivity, laboratory animals, chemicals, and lasers. Employee is expected to wear appropriate protective equipment such as gloves, coat, and eyewear and conform to the university’s protocols for safety.
Case Western Reserve University's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.Diversity Statement
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.