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Research Assistant 3

Employer
Case Western Reserve University
Location
Case Main Campus

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Job Details

Job Title: Research Assistant 3
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8487
Job Description POSITION OBJECTIVE

Working under limited supervision of the principal investigator, the Research Assistant 3 will carry out complex research assignments of a non-routine nature. The research assistant will utilize new and innovative research techniques involving a high degree of skill and training. The lab’s research is in the field of protein-protein and protein-membrane interactions and examines molecular level mechanisms of cell signaling in several systems.

ESSENTIAL FUNCTIONS

    Coordinate research activities. Serve as lab manager, order consumables and interact with the administration concerning lab safety. (10%)Carry out protein and peptide expression and purification from E. coli and possibly from insect or mammalian cells. Set up in vitro peptide translation/optimization system. (28%)Perform protein-protein and protein-lipid interaction studies using vars biophysical techniques. (18%)Devise protocols and techniques for research projects with guidance from the principal investigator and literature on other or related systems. Optimize and assess these protocols for their efficiency/sample and data yield. (13%)Train new staff and students. (13%)Will likely co-author research publications and attend/present at conferences. (8%)

NONESSENTIAL FUNCTIONS

    Evaluate adequacy of techniques used in terms of signal to noise, number of repetitions/samples needed to reach statistical significance; study and test new procedures and analyze data. (5%) Prepare stock solutions. May occasionally communicate/ship reagents to collaborators or external parties. Perform other duties as assigned. (5%)

CONTACTS

Department: Frequent contact with supervisor to discuss research and laboratory status.

University: Occasional contact with other departments to share information.

External: Occasional contact with vendors to exchange information.

Students: Daily contact with student employees to share information.

SUPERVISORY RESPONSIBILITY

Training of new staff and students.

QUALIFICATIONS

Experience: 3 to 5 years of related experience required.

Education: Bachelors of Science required. Masters of Science or Ph.D. of Science degree in related field preferred.

REQUIRED SKILLS

    Experience in several biophysics techniques to characterize protein-protein and protein lipid interactions, e.g. ITC, SPR, MST, AUC, SEC-MALS.Conceptual understanding of proteins and peptide structure. Major in Biochemistry or Molecular Biology.Experience with protein expression and purification, including use of FPLC and/or HPLC.Strong organizational skills required for maintaining records of research and lab supplies/reagents. Ability to multi-task, prioritize and give attention to detail in order to complete tasks and meet deadlines.Good verbal, presentation and written communication skills.Good interpersonal skills, ability to work and communicate with various individuals within the department, school and university, and with individuals outside the University.Ability to work effectively, independently and collaboratively within a team.Must be able to deal with some shifts in priorities, demands and timeline. Must be flexible in order to respond to project adjustments and alterations promptly and efficiently. Ability to follow-through on assigned projects and provide timely follow-up as needed.Technical competence with software applications such as Microsoft Office, Excel, Photoshop, Origin or other data plotting software, database applications, and with internet navigation. Ability to learn and apply software programs and applications as needed.Ability to meet consistent attendance.Ability to interact with colleagues, supervisors, collaborators and customers face to face.

WORKING CONDITIONS

The employee will be working with general chemicals and will need to take Chemical Safety Training. A standard lab coat, gloves, and safety glasses will be provided. This position will not work with animals or pathogenic agents.

Organization

Working at Case Western Reserve University

Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in educationresearch, service and experiential learning. Located in Cleveland's University Circle, we offer nationally recognized programs in the arts and sciencesdental medicineengineeringlawmanagementmedicinenursing and social sciences.

Student enrollment exceeds 9,800 students, forty percent of whom are undergraduatesFacultyand students hail from more than 90 countries, with academic interests that reach every region of the world. Case Western Reserve, with the support of individuals, corporations and foundations, aids nearly 100 designated research centers.

As a service-oriented institution dedicated to civic leadership, Case Western Reserve seeks individually and collectively to prepare our students to improve the human condition and to direct the benefits of discovery toward a better society. This effort is not limited to the university's classrooms, laboratories, librariesresidence halls and athletic fields, but includes partnerships with many other institutions. We build these partnerships believing that our ability to improve the human condition should begin in our own community.

Case Western Reserve University remains Ohio's top-ranked school among the nation's premier national universities, as ranked by U.S. News & World Report and is the only Ohio institution ranked in the top 50 nationally. We promote a culture of inquiry marked by rigor, creativity, curiosity, innovation, respect, sensitivity and open communication of ideas.

The university supports interdisciplinary partnerships in education and research with numerous faculty holding joint appointments in more than one Case Western Reserve school or department, as well as at neighboring institutions. These relationships launched many of the unique pairings of science, business and liberal arts into the centers and programs that enhance the undergraduate and graduate experience at the university. Our dual degree programs enrich the educational experience for those students who choose to balance the technical requirements of engineering or the sciences with a strong interest in the humanities.

With more than $375 million in research funding annually, the university attracts outstanding undergraduate and graduate students along with renowned faculty whose research has made significant contributions to the way we live and work. Case Western Reserve counts 15 Nobel laureates among our alumni and current and former faculty, including the first American scientist to ever receive the prize.

Our students' experiences in cultural institutions, clinics, social service agencies and industry are not viewed as “extra-curricular,” but create the learning experience that defines a Case Western Reserve education. The university's service programs in the Cleveland Municipal School District have impacted more than 145,000 students with more than 43 signature programs. The university has launched more than 580 community partnerships on the local, national and international levels. Annually the university sponsors Case for Community Day, an event where hundreds of Case Western Reserve employees and students lend their time and talent to targeted community development projects in the Greater Cleveland area.

Our alumni number more than 110,000 and constitute a “who's who” of every profession. Alumni represent one of the university's strongest resources, playing a vital role in campus life through their work as advisors, mentors, friends and advocates.

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