Research Assistant 3

Job description

Job Title: Research Assistant 3
Location: Case Main Campus
Regular/Temporary: Regular
Full/Part Time: Full-Time
Job ID: 8487

Working under limited supervision of the principal investigator, the Research Assistant 3 will carry out complex research assignments of a non-routine nature. The research assistant will utilize new and innovative research techniques involving a high degree of skill and training. The lab’s research is in the field of protein-protein and protein-membrane interactions and examines molecular level mechanisms of cell signaling in several systems.


    Coordinate research activities. Serve as lab manager, order consumables and interact with the administration concerning lab safety. (10%)Carry out protein and peptide expression and purification from E. coli and possibly from insect or mammalian cells. Set up in vitro peptide translation/optimization system. (28%)Perform protein-protein and protein-lipid interaction studies using vars biophysical techniques. (18%)Devise protocols and techniques for research projects with guidance from the principal investigator and literature on other or related systems. Optimize and assess these protocols for their efficiency/sample and data yield. (13%)Train new staff and students. (13%)Will likely co-author research publications and attend/present at conferences. (8%)


    Evaluate adequacy of techniques used in terms of signal to noise, number of repetitions/samples needed to reach statistical significance; study and test new procedures and analyze data. (5%) Prepare stock solutions. May occasionally communicate/ship reagents to collaborators or external parties. Perform other duties as assigned. (5%)


Department: Frequent contact with supervisor to discuss research and laboratory status.

University: Occasional contact with other departments to share information.

External: Occasional contact with vendors to exchange information.

Students: Daily contact with student employees to share information.


Training of new staff and students.


Experience: 3 to 5 years of related experience required.

Education: Bachelors of Science required. Masters of Science or Ph.D. of Science degree in related field preferred.


    Experience in several biophysics techniques to characterize protein-protein and protein lipid interactions, e.g. ITC, SPR, MST, AUC, SEC-MALS.Conceptual understanding of proteins and peptide structure. Major in Biochemistry or Molecular Biology.Experience with protein expression and purification, including use of FPLC and/or HPLC.Strong organizational skills required for maintaining records of research and lab supplies/reagents. Ability to multi-task, prioritize and give attention to detail in order to complete tasks and meet deadlines.Good verbal, presentation and written communication skills.Good interpersonal skills, ability to work and communicate with various individuals within the department, school and university, and with individuals outside the University.Ability to work effectively, independently and collaboratively within a team.Must be able to deal with some shifts in priorities, demands and timeline. Must be flexible in order to respond to project adjustments and alterations promptly and efficiently. Ability to follow-through on assigned projects and provide timely follow-up as needed.Technical competence with software applications such as Microsoft Office, Excel, Photoshop, Origin or other data plotting software, database applications, and with internet navigation. Ability to learn and apply software programs and applications as needed.Ability to meet consistent attendance.Ability to interact with colleagues, supervisors, collaborators and customers face to face.


The employee will be working with general chemicals and will need to take Chemical Safety Training. A standard lab coat, gloves, and safety glasses will be provided. This position will not work with animals or pathogenic agents.




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Job No:
Posted: 10/6/2020
Application Due: 12/5/2020
Work Type: