Job location: Charlottesville, VA
Employment Type: Full-time
Posted data: 2021-02-23
The Arandjelovic lab in the Department of Medicine, Division of Nephrology & Center for Immunity, Inflammation & Regenerative Medicine at the University of Virginia is seeking a post-doctoral Research Associate to join the team studying cell clearance/phagocytosis in inflammation, with focus on arthritis models. Apoptotic cells are frequently observed at sites of ongoing inflammation, and inefficient clearance of apoptotic cells can lead to secondary necrosis and the release of their cellular contents, which can further fuel the inflammatory process. However, the nature of dying cells, the cellular identity of phagocytes and the molecular events that contribute to clearance of apoptotic cells have been understudied in many inflammatory diseases, including arthritis. In other words, “who” are the cleaning crew and which “tools” are they using?
In the Arandjelovic lab, we focus on addressing the following questions:
1. Who are the phagocytes in the healthy and inflamed joints?
2. What are they “eating” (infiltrating leukocytes, tissue resident cells)?
3. Does modulation of cell clearance pathways impact disease parameters?
These studies will identify new modulators of inflammatory and autoimmune disease and uncover novel pathways that can be targeted for therapeutic benefit.
Qualified applicants must have an M.D. and/or Ph.D. in Immunology, Cell Biology, Physiology or a related field before the start date. The candidate is expected to have at least one first-authored publication in a peer-reviewed journal, and demonstrated skills must include the use of techniques in cell and molecular biology such as cell culture, functional, biochemical and cell-based assays. Extensive experience in basic immunology, flow cytometry, and microscopy is required. Experience with big data set analyses is preferred. The ability to work independently, as well as interact with diverse groups of scientists and students is essential. This is a restricted position; continuation is dependent on funding and satisfactory performance.
The University of Virginia is located in Charlottesville, Virginia nestled among the Blue Ridge Mountains, and offers a quality of life unparalleled in the United States. The community and surrounding areas are steeped in the history and heritage of America and there is easy access to some of the country's most vibrant cities. Washington, DC is just a short train/car ride away! Residents have access to outstanding theater, fine arts, music, sports, shopping, and restaurants representing cuisines from around the World. The outdoor living in and around Charlottesville is second to none! Charlottesville is serviced by an easily accessible airport that is the jumping off point for destinations around the globe. Our city is growing and economically robust. It is safe and affordable, enabling all of the advantages of cosmopolitan living removed from the challenges of big city living. It is a wonderful place to raise a family.
For additional information please contact Dr. Sanja Arandjelovic at email@example.com, or call 434-924-1875.
To apply please visit UVA job board https://uva.wd1.myworkdayjobs.com/UVAJobs, and search for "R0017700". Complete the application and see below for documents to attach. Please note that multiple documents can be uploaded in the CV/Resume box.
Required Application Materials:
- Cover Letter
- Contact for 3 references
Please note multiple documents can be submitted in the CV/Resume Box. Applications that do not contain all of the required documents will not receive full consideration.
The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.