Senior Professional Research Assistant

Job description


University of Colorado – School of Medicine

Senior Professional Research Assistant

Linda Crnic Institute for Down Syndrome, School of Medicine


The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment.  We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

Jobs in this career family provide direct professional support of research activities.  Functions include research animal management, research laboratory coordination and instruction, environmental health and safety, radiation control, hazardous materials use, disposal and training.

The Linda Crnic Institute for Down Syndrome is searching for a Senior Professional Research Assistant to work in the Crnic Institute’s Mouse Models Facility. The position involves leading the maintenance and management of a mouse colony composed of several models of Down syndrome; design, execution, and analysis, of experiments in these mouse models. The qualified candidate will work to maintain the mouse colony and, and independently perform experiments using various mouse models of Down syndrome.

Duties and Responsibilities

  • Mouse handling, behavioral training/testing, euthanasia
  • Establish baseline differences in cognitive abilities using mouse models of Down syndrome
  • Analyze the impact of immune dysregulation on cognitive abilities in mouse models of Down syndrome
  • Analysis of neuroprotective and therapeutic effects of pharmaceuticals after immune stimulation
  • Functional and molecular assays
  • Develop and maintain research databases
  • Data analysis, presenting, and publishing findings
  • Communicate with PI to help manage efforts of a team of researchers
  • Train junior team members
  • Animal imaging
  • Experienced researchers are encouraged to apply for this PRA position

Salary and Benefits:

Salary is commensurate with skills and experience. The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.



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Diversity and Equity:

Please click here for information on disability accommodations:

Office of Equity:

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

QualificationsMinimum Qualifications

  • Master's degree in biology, chemistry or related sciences
  • At lease two years experience with animals (preferably with mouse models) and various molecular biology techniques (PCR, pipette sterile technique, chemical storage and disposal, etc.)
 Applicants mustmeet minimum qualifications at the time of hire.


  • Ability to perform essential mouse experimental techniques (injections, oral gavage, whole body necropsy, etc.)
  • Ability to work both independently and as a team member, with supervision of a principal investigator and current laboratory staff
  • Mouse colony management, handling, and testing of mice
  • Self-motivated; highly organized, with demonstrated project planning and management skills in an academic research setting
  • Knowledge about developmental and cognition assays in mice (open field, rotarod, context fear conditioning, etc.)
  • Working knowledge of molecular biology techniques for protein, RNA and DNA analysis
  • Strong quantitative analysis skills, including statistics; excellent written and oral communication skills, and strong word processing skills
  • Ability to develop new techniques and methods through literature searches
  • Proven self-initiative and ability to catalyze new projects or ideas
  • Exceptional organizational and time management skills, ability to manage multiple projects or requests.
  • Excellent written and verbal communication skills
  • Positive attitude and the ability to work with a variety of biomedical investigators and colleagues.
  • Ability to contribute to the growth and development of the Linda Crnic Institute and the Mouse Models Facility

Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Sep 15, 2020
Unposting Date: Ongoing




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Job No:
Posted: 9/18/2020
Application Due: 12/31/2020
Work Type: