Resource Technologist B, Next Generation Sequencing

Job description

Resource Technologist B, Next Generation Sequencing

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title
Resource Technologist B, Next Generation Sequencing

Job Profile Title
Resource Technologist B

Job Description Summary
The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the "go-to" organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

Continuation of all GTP positions are contingent upon funding.

Job Description

The Nucleic Acid Technologies Core (NAT) at GTP utilizes a variety of cutting-edge Next-Generation Sequencing (NGS) technologies to serve both the Discovery and Translational research teams. Processing hundreds of samples a month, the core provides both sequence and data analysis for on- and off-target genome editing assays, protein engineering libraries, genomics applications, plasmid sequencing, and vector genome sequencing.

We are actively recruiting a Resource Technologist B to support the efforts of the NAT Core.

As a Resource Technologist B, you will perform a wide range of moderate to complex high-throughput Next-Generation Sequencing (NGS) techniques, including DNA extraction, quantification, fragmentation, quality assessment, PCR, qPCR, Illumina and Oxford Nanopore sequencing. You will also Collect, analyze and interpret quality control metrics from NGS QC instruments, including ultrasonicators, spectrophotometers, fluorometers and high-resolution automated capillary electrophoresis platforms. Data analysis will be performed under the guidance of a staff Bioinformatician.


  • BS degree in molecular biology or related field required required
  • 3-5 years relevant laboratory experience required
  • Knowledge of molecular biology methods is required
  • Demonstrated ability to perform high-throughput laboratory techniques such as multichannel pipetting and microplate manipulation is highly desired
  • Next- generation sequencing experience is desired
  • Independent thinker, meticulous, detail-oriented, and analytical. Excellent time management skills are essential.
  • Ability to work as part of a team
  • Excellent oral/written communication skills required

    Job Location - City, State
    Philadelphia, Pennsylvania

    Department / School
    Perelman School of Medicine

    Pay Range
    $42,953.00 - $77,315.00

    Affirmative Action Statement
    Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

    Special Requirements
    Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

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    Job No:
    Posted: 9/10/2020
    Application Due: 11/9/2020
    Work Type: