Postdoctoral Research Associate I (College of Medicine-Phoenix)

Location
Tucson, AZ
Posted
Aug 31, 2020
Position Type
Postdoc
Institution Type
Four-Year Institution
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The Department of Internal Medicine at the University of Arizona College of Medicine-Phoenix seeks a Postdoctoral Research Associate in the laboratory of Dr. Timothy Marlowe. The successful candidate will be invited to join a collaborative drug discovery research team, working on the discovery and development of novel therapeutics for cancer. The primary goal of Dr. Marlowe’s translational research program is to identify and evaluate inhibitors of focal adhesion kinase (FAK) by creating novel FAK-scaffold inhibitors. We are seeking a highly motivated individual with a Ph.D. in Medicinal Chemistry or Organic Chemistry with a strong background in both peptide and small molecule chemistry, drug design, synthesis, and medicinal chemistry. The candidate should have experience in pharmaceutical approaches to peptide and small molecule drug development in cancer as well as excellent written and verbal communication skills. Experience with structure-based drug design, peptide/peptidomimetic design, fragment-based drug design and novel medicinal chemistry approaches for drug design and organic synthesis is required.

As a cost-saving measure related to the impact of COVID-19, Furlough and Furlough-Based Salary Programs have been approved by the Arizona Board of Regents. All new hires subject to the programs will be notified in accordance with adopted Furlough and Furlough-Based Salary Programs guidelines and will be required to comply with all measures. To learn more about the programs and whether this position is affected, please visit hr.arizona.edu/FY-2020-2021-Furlough-Program.

Outstanding UA benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state and optional retirement plans; access to UA recreation and cultural activities; and more!

Duties & Responsibilities
  • Perform independent research experiments under the direction of the principal
    investigator.
  • Contribute to grant writing, manuscript preparation and participation at scientific
    conferences.
  • Design and perform experiments, interpret data, and analyze results.
  • Work collaboratively with NMR and X-Ray Crystallographic colleagues to perform
    structure-based drug design.
  • Design and synthesize lead compounds, peptides, and tether fragment hits.
  • Coordinate with pharmacologists and develop structure-activity relationship.s
  • Review in silico drug searches for appropriate drug-like compounds.
  • Develop and maintain detailed records of experiments, analyzing and writing findings.
  • Develop and implement protocols as dictated by experimental results.
  • Maintain internal chemical databases.
  • May supervise laboratory staff and manage laboratory purchasing as needed.
  • Other duties may be assigned.

Knowledge, Skills, & Abilities

  • Skilled in coordinating experiments.
  • Knowledge of manuscript preparation.
  • Ability to participate at scientific conferences and present findings.

 

Minimum Qualifications
  • PhD in an area of organic chemistry, medicinal chemistry, or related field.
  • Strong background in drug optimization and cancer drug development.
Preferred Qualifications
  • First author publications with a strong background in drug design and discovery.
  • Experience in both traditional organic chemistry and solid phase peptide synthesis.
  • Strong motivation and dedication to scientific discovery is essential.
  • Demonstrated ability to independently develop reports and manuscripts and present findings in tabular, oral, written, and/or graphic formats.
  • FLSA Exempt Full Time/Part Time Full Time Number of Hours Worked per Week 40 Job FTE 1.0 Work Calendar Fiscal Job Category Research Benefits Eligible Yes - Full Benefits Rate of Pay NIH salary guidelines, Depends on Experience Compensation Type salary at 1.0 full-time equivalency (FTE) Type of criminal background check required: Fingerprint criminal background check (security sensitive due to title or department) Number of Vacancies 1 Target Hire Date 10/18/2020 Expected End Date Contact Information for Candidates College of Medicine-Phoenix, Office of Human Resources Open Date 8/11/2020 Open Until Filled Yes Documents Needed to Apply Curriculum Vitae (CV) and Cover Letter Special Instructions to Applicant
    Application: The online application should be completed in its entirety. Blank or missed information may be considered an incomplete submission.

    Letter of Interest: Should clearly indicate how your skills and professional employment experience meet the Minimum and the Preferred qualifications (if applicable).

    References: Please list 3 professional references including address, title, phone and email address.
    Diversity Statement At the University of Arizona, we value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community. As an Hispanic-serving institution, we translate these values into action by seeking individuals who have experience and expertise working with diverse students, colleagues, and constituencies. Because we seek a workforce with a wide range of perspectives and experiences, we provide equal employment opportunities to applicants and employees without regard to race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity, or genetic information. As an Employer of National Service, we also welcome alumni of AmeriCorps, Peace Corps, and other national service programs and others who will help us advance our Inclusive Excellence initiative aimed at creating a university that values student, staff and faculty engagement in addressing issues of diversity and inclusiveness.

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