Post Doc Fellow

Department of Cancer Biology

University of Cincinnati College of Medicine

The Department of Cancer Biology at the University of Cincinnati has an opening for a Postdoctoral Fellow to study transcriptional and epigenetic regulation of gene expression in breast cancer. The Zhang laboratory currently focuses on elucidating molecular mechanisms of gene- and tissue- specific transcriptional cofactors and small RNAs (e.g. miRNA, enhancer RNA) in breast cancer [Mol Cell 19:89-100, PNAS 107: 6765, JBC 286:17746, EMBO J. 30:2405, Cancer Research 72:5625, ACS Nano 11(1):335, Cancer Research 78(2):422, Estrogen Receptor and Breast Cancer – Celebrating the 60th Anniversary of the Discovery of ER (1st ed, 2019, Springer Nature)]. We are using a combination of biochemical, molecular, genomic and mouse genetic (conditional knockout, mutant knockin and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome therapeutic resistance of human breast cancer. This temporary appointment shall not exceed five(5) years; however, short extensions may be granted when necessary to complete a critical research project.

Primary Duties:

• Perform and conduct research required by faculty supervisor to a high standard and in accordance with all institutional and federal regulations.
• Engage in appropriate training and professional development opportunities.
• May support the development of proposals for research-related funding and grants.
• Engage in the dissemination of the results of the research as directed by and with the support of associated faculty members.
• Communicate to project team progress and results of research activities ensuring that relevant information and issues in the implementation of projects/experiments are captured in as comprehensive and timely manner as possible.
• Play an active role in seeking career and research advice, both from the faculty supervisor and from other faculty members as well.

Minimum Requirements:

• Ph.D., M.D., or M.D./Ph.D., required.
• Requires an in-depth knowledge of biochemistry, molecular cellular biology or a related field.
• Good oral and written communication skills.
• Ability to work and collaborate effectively with students, faculty and staff from a variety of culturally diverse backgrounds.

Ideal Qualifications:

• Prior experience with animal studies or small RNAs is a plus.
• Research experience in biochemistry, molecular cellular biology or a related field.

The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.

As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).

The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / M / F / Veteran / Disabled.

REQ: 40106

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