Postdoctoral Research in Neuron-Glial Interactions

Job description

Postdoctoral Research in Neuron-Glial Interactions
University of California, Los Angeles

Requisition Number: JPF04996
Recruitment Period
Open date: September 18th, 2019
Last review date: Friday, Nov 1, 2019 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Friday, May 1, 2020 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.


How do microglia shape normal and pathological circuit function?
Microglia are dynamic, macrophage-like cells within the CNS. They remove cellular debris and pathogens from surrounding tissue and exert powerful neuroprotective and/or neurotoxic effects during disease and injury. They can also modulate neuronal membrane properties and synapses, positioning these cells as key contributors to physiological and pathological circuit function. Microglia are not equivalent throughout the brain and exhibit specialized phenotypes in different nuclei of the basal ganglia (BG), circuits involved in reward and motivation. We exploit these regionally specialized phenotypes to study how microglial variation shapes synaptic function, resilience, and viability of BG neurons. We also exploit this regional specialization of microglia to identify cues that regulate basal microglial phenotypes to discover novel strategies for manipulating microglial properties. Visit for more information.

We are hiring highly motivated PhD neuroscientists or cellular biologists to study dynamic features of microglial cells and how such properties impact neuronal and circuit function. We seek candidates with a strong background in confocal or multiphoton imaging. We also welcome candidates who excel in one of the following areas: slice electrophysiology, molecular biology, next generation sequencing, organotypic slice culture, dissociated cell culture and viral transfection. PhD must be expected within 6-9 months.

Please send a cover letter, current CV, and contact info for three references to: [email protected].

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The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy,





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Job No:
Posted: 9/20/2019
Application Due: 1/14/2020
Work Type: