Post-Doctoral Fellow (Theiss Lab)

Job description


Universityof Colorado – School of Medicine

Post-Doctoral Fellow (Theiss Lab) 

The University of ColoradoDenver l Anschutz Medical Campus seeks individuals with demonstrated commitmentto creating an inclusive learning and working environment.  We value theability to engage effectively with students, faculty and staff of diversebackgrounds.

The University ofColorado’s Division of Gastroenterology and Hepatology in the Department ofMedicine, located at the Anschutz Medical Campus, is an internationallyrenowned program that provides comprehensive resources for the diagnosis andtherapy of diseases of the digestive tract, pancreas and liver.  The Division of Gastroenterology andHepatology has faculty and staff making contributions to research, clinicaltrials, and nationally recognized patient care. Gastroenterology & GI Surgery is one of the top ranked in the UnitedStates and our clinical partner, the University of Colorado Hospital, and is inthe top hospitals nationwide as ranked by U.S. News and World Report. TheDivision of Gastroenterology and Hepatology is rapidly growing, with clinicalpractices throughout the state of Colorado and over 80 researchers, physiciansand staff, all working toward its vision to prevent and treat disease whilebeing a global model for patient care delivery, interdisciplinary research, andtraining.

 As an importantmember of the basic science research team, the post-doctoral fellow will workon projects related to mitochondrial dysfunction/mitophagy and intestinalinflammation.  This position will be part of the Mucosal InflammationProgram, a collaborative research program at the University of Colorado thatintegrates basic and clinical science with the goal of determining mechanismsof inflammation in a variety of mucosal surfaces including the GI tract and thelung. This multidisciplinary approach fosters collaboration between keypersonnel from different departments and divisions of the School of Medicine toprovide outstanding patient care and novel research outcomes.

 Thisposition reports directly to Arianne Theiss, PhD, Associate Professor, and isresponsible for developing, executing and analyzing data from research projectsaimed at understanding the role of mitochondrial stress in the development ofintestinal inflammation. This position is an opportunity for a bright, creativeand enthusiastic individual to advance their career by performing impactful,cutting-edge biomedical research in an exciting field of study.

 Thereis no direct patient care and no patient contact involved in thisposition.  There are no supervisoryduties associated with this position.

Examples of Work PerformedThis position will work independentlyunder the guidance of the principal investigator.  Work will involve designing, planning, andexecuting experiments to better understand how changes in mitochondrial healthinfluence inflammation within the intestine using models of inflammatory boweldisease (IBD) and human IBD specimens. Specific duties include:

  • Utilizingmolecular biology and genomic analysis techniques to elucidate mitophagysignaling in the intestinal epithelium
  • Design and implement projects relating to the laboratory’s overall research program.
  • Analyze, interpret, and fully document experimental results
  • Operate and maintain laboratory equipment
  • Prepare data and manuscripts for publication
  • Prepare grant proposals to obtain independent post-doctoral funding
  • Actively participate in and present data at group meetings, journal clubs and conferences
  • Work in conjunction with the PI and other lab staff to achieve programmatic goals
  • Meetwith the project PI on a weekly basis for the purpose of progress updates andmentoring
  • Other duties as assigned
Thisdescription is a summary only and is describing the general level of work beingperformed; it is not intended to be all-inclusive. The duties of this positionmay change from time to time and/or based on business need. We reserve theright to add or delete duties and responsibilities at the discretion of thesupervisor and/or hiring authority.

Salary and Benefits: Salary iscommensurate with skills and experience. The University of Colorado offers afull benefits package. Information on University benefits programs, includingeligibility, is located at Employee Services.

 University ofColorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe andsecure environment for our faculty, staff, students and visitors. To assist inachieving that goal, we conduct background checks for all new employees priorto their employment.

 The ImmigrationReform and Control Act requires that verification of employment eligibility bedocumented for all new employees by the end of the third day of work. Alternativeformats of this ad are available upon request for persons with disabilities.

 Yourtotal compensation goes beyond the number on your paycheck. The University ofColorado provides generous leave, health plans and retirement contributionsthat add to your bottom line.

  Benefits: Calculator:

 Diversityand Equity:

 Pleaseclick here for information on disability accommodations: 

 TheUniversity of Colorado Denver | Anschutz Medical Campus is committed torecruiting and supporting a diverse student body, faculty and administrativestaff. The university strives to promote a culture of inclusiveness, respect,communication and understanding. We encourage applications from women, ethnicminorities, persons with disabilities and all veterans. The University ofColorado is committed to diversity and equality in education and employment.

QualificationsMinimum Requirements
  • Adoctoral level degree (PhD, MD, MD/PhD) in cell biology, molecular biology, immunology,or related field from an accredited institution.
  • Atleast one first-author publication in an internationally recognized,peer-reviewed journal.
Conditionsof Employment:

  • Candidatemust be willing and able to work with laboratory animals and animal tissues.
  • Candidatemust be willing and able to work with human tissues.
  • Candidatemust meet eligibility requirements for NIH T32 and F32 postdoctoral fellowshipawards.
Preferred Qualifications
  • Graduatetraining in a biomedical laboratory setting, studying epithelial or stem cellbiology, immunology, and/or molecular biology
  • Experiencein laboratory animal handling, husbandry and dissection
  • Experiencewith mitochondrial signaling pathways
  • Experiencewith molecular biology, biochemistry, and/or cell or enteroid culturelaboratory techniques
Knowledge, Skills and Abilities
  • Abilityto communicate effectively, both in writing and verbally.
  • Abilityto establish and maintain effective working relationships with employees at alllevels throughout the institution.
  • Demonstratedcommitment and leadership ability to advance diversity and inclusion.
  • Excellentorganizational skills, ability to problem-solve, multi-task, and workindependently.
  • Goodcommand of the English language, both written and verbal.
  • Excellentattention to detail.
  • Abilityto work independently and as a team member within a research environment.
  • Abilityto work efficiently and effectively with computer software, including MicrosoftOffice.
  • Skilledwith the use of aseptic mammalian cell culture techniques.
  • Skilledwith common laboratory techniques and equipment consistent with PhD-levelgraduate training.
  • Abilityto commit to an independent scientific career in epithelial cell biology, immunology,or a related field, with a proven high degree of independence andself-motivation to achieve these ends.
  • Abilityto interpret and comprehend complex information.
  • Knowledgeof basic human anatomy, physiology, medical terminology.

Job Category: Faculty
Primary Location: Aurora
Schedule: Full-time
Posting Date: Aug 19, 2019
Unposting Date: Ongoing




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Job No:
Posted: 8/21/2019
Application Due: 9/20/2019
Work Type: