Post Doctoral Scholar
- Employer
- University of Kentucky
- Location
- Lexington, KY
View more
- Administrative Jobs
- Institutional & Business Affairs, Auxiliary Services
- Position Type
- Postdoc
- Employment Type
- Full Time
- Institution Type
- Four-Year Institution
Job Details
PhD or MD/PhD in an area relevant to pharmacology or neuroscience
Required Related ExperiencePrior experience in AD, TBI, or related neurological disease research is also desirable.
Required License/Registration/Certificationn/a
Physical RequirementsMay require long periods of sitting and/or standing. May require lifting up to 25lbs.
ShiftPrimarily days but some nights and weekends may be required
Job SummaryA postdoctoral scientist position is available immediately at the University of Kentucky, Lexington KY. The position is in the Sanders-Brown Center on Aging, an established research center in aging and dementia where independent basic and clinical scientists work in a collaborative environment. The Center on Aging also includes the NIH-funded Alzheimer’s Disease Center that provides unique and outstanding resources to support innovative research (e.g. longitudinally followed and well-characterized clinical cohorts, neuroimaging, biomarkers, autopsy specimens). Our Center has recently completed the first tier in state-of-the-art upgrades in core equipment and facilities to enable access to multiphoton in vivo imaging, cell sorting, single-cell transcriptomics, high-speed confocal imaging, multiplex tissue spatial profiling, and mouse behavioral phenotyping, to name a few. Postdocs can also collaborate with a number of other centers at the university that facilitate neuroscience research, including the Spinal Cord and Brain Injury Research Center, the Magnetic Resonance Imaging and Spectroscopy Center, the Center for Clinical and Translational Science, and the Kentucky Neuroscience Institute.
The successful candidate will benefit from an experienced mentor, a stimulating and collaborative research environment, and an organized training plan to propel their future career goals. There are ample opportunities for scientific growth, career enhancement, and development into an independent investigator in academia, industry, or other career paths. Although the project is currently funded by NIH, an integral part of postdoctoral training is the process of preparing a research proposal and writing a fellowship application, so postdocs are encouraged to apply for external funding when possible. Postdocs will also be eligible for applying to our Center’s T32 training program, which focuses on diseases of the aging brain. Moreover, postdocs from our lab have a consistent track record for obtaining NIH-funded F32 and K99/R00 awards, which provides recognition for both the fellow and the Center on Aging.
We seek a highly motivated, creative, and collaborative individual to work on mechanistic and translational research projects focused on the detrimental inflammatory and neurodegenerative responses that contribute to pathophysiology in a mouse model of comorbid Vascular Contributions to Cognitive Impairment and Dementia (VCID) and Alzheimer’s disease (AD). A component of this project will utilize a novel brain-penetrant small molecule as an anti-inflammatory strategy to combat inflammatory-related pathophysiology to determine optimal dosing and timing in the comorbid disease environment. Anticipated approaches to delineate comorbid pathophysiology response will include a multifaceted approach harnessing multiphoton vascular imaging in intact animals, flow cytometry and cell sorting for transcriptional profiling, as well as cognitive phenotyping.
Skills / Knowledge / AbilitiesMust have excellent interpersonal, organizational, verbal and written communication skills, a solid publication record, and appropriate experience.
Does this position have supervisory responsibilities? No Preferred Education/ExperiencePreference will be given to individuals with experience in one of the following areas: inducible conditional knockout mouse models, mouse neuropathology and behavior, primary glia/neuron cell culture, gene expression profiling, pharmacological modulation of glia signaling pathways
Deadline to Apply 04/26/2019 University Community of InclusionThe University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus.
As an Equal Opportunity Employer, we strongly encourage veterans, individuals with disabilities, women, and all minorities to consider our employment opportunities.
Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.
Required fields are indicated with an asterisk (*).
- Curriculum Vita
- Cover Letter
Organization
Fast Facts
Location: Lexington, Ky.
Founded: 1865
Endowment: $1.1 billion
Budget: $3.5 billion
Research Grants and Contracts Awarded: $316.5 million
Library Holdings: 4.3 million volumes
Enrollment: 30,76
President: Dr. Eli Capilouto
Provost: Dr. David W. Blackwell
Executive Vice President for Finance and Administration: Dr. Eric Monday
Executive Vice President for Research: Dr. Lisa A. Cassis
Executive Vice President for Health Affairs: Dr. Mark F. Newman
About the University
Adjacent to downtown Lexington, UK is nestled in the scenic heart of the beautiful Bluegrass Region of Kentucky. UK's campus covers more than 814 acres, with more than 30,700 students and 13,500 full-time employees, including nearly 2,400 full-time faculty and librarians.
Mission
The University of Kentucky is a public, land grant university dedicated to improving people's lives through excellence in education, research and creative work, service, and health care. As Kentucky's flagship institution, the University plays a critical leadership role by promoting diversity, inclusion, economic development, and human well-being.
Our Guiding Principles
The University is driven by the promise it has made to Kentucky, one that honors its land-grant mission and a heritage honed through 150 years of service to the Commonwealth of Kentucky. Six principles guide our efforts. They are: creating a vibrant undergraduate learning community, advancing a high-quality graduate and professional education portfolio, cultivating a robust research environment, developing a strong and sustainable UK infrastructure, fostering a positive work environment for faculty and staff, and ensuring a meaningful impact on the Commonwealth and the community.
Employment/Benefits
As Central Kentucky's largest employer, the University of Kentucky supports the recruitment and retention of unparalleled talent - individuals who inspire learning, teaching, service and healing through innovation in work solutions, initiatives, policies and programs. Impressive benefits at the University include an excellent retirement package, with an employer match that doubles the employee's contribution, a dynamic work-life program to assist employees in balancing their work with their personal lives, a wellness program to protect, maintain and promote the health of employees, and a strategic plan that nurtures diversity of thought, culture, gender and ethnicity. For more information regarding benefits, visit http://www.uky.edu/hr/benefits.
Research
In fiscal year 2016, the University of Kentucky was awarded $316.5 million in external grants and contracts. UK is one of only eight universities across the country with the full range of undergraduate, graduate, professional and medical programs on one contiguous campus, leading to groundbreaking discoveries and unique cross-disciplinary research and scholarship. Moreover, UK is currently one of only 22 public institutions with a trifecta of federal designations of excellence in research: for aging, in cancer and in translational science. A new $265 million research facility, due to open in 2018, will bring together clinicians, scientists and scholars from across UK’s campus to reduce health gaps in Kentucky. These health gaps include cancer, cardiovascular disease & stroke, diabetes & obesity, substance abuse, and neuroscience & aging.
Research at UK is a dynamic enterprise encompassing both traditional scholarship and emerging technologies. UK is one of eight universities in the U.S. that has well-established programs in agriculture, engineering, medicine and pharmacy on a single campus, leading to groundbreaking discoveries and unique interdisciplinary collaboration.
In 2013, the UK Markey Cancer Center announced its designation as a National Cancer Center by the National Cancer Institute. This designation places UK among an elite group of 22 research universities that can boast the "Triple Crown" of federal research awards: NCI designation, the Clinical Translational Sciences Award, and a federally supported Alzheimer's Disease Center.
UK HealthCare
UK HealthCare has strategically developed an incredible capacity to serve the Commonwealth through its state-of-the-art patient care pavilion and emergency rooms, advanced biomedical and biological research, and a network of affiliate health care agencies throughout Kentucky. Passion for people and a vision for the "medical campus of the future" have inspired leading physicians and researchers from across the United States to join UK. Their research agenda is balanced with outreach to affiliated and partner hospitals, so Kentucky families can receive high-quality health care at home and travel to Lexington for only the most advanced, complex medical care and procedures.
Living in the Bluegrass
Ranked as one of the nation's best places to live and work, Lexington offers many diverse educational, cultural and commercial opportunities. With a population of more than 314,000 people, Lexington supports cultural attractions such as opera, ballet, theater and musical events. Surrounded by rolling hills and horse farms, the Bluegrass Region is known for its natural beauty. For more information: http://www.uky.edu/hr/employment/working-uk/life-in-lexington.
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