Post Doctoral Fellow - Center for Human Genetics

Job description

Post Doctoral Fellow - Center for Human Genetics

Location:
Clemson Center for Human Genetics, Self Regional, 114 Mendal Circle, Greenwood, SC 29646
Open Date:
Apr 4, 2019
Description:

The laboratories of Trudy Mackay and Robert Anholt at the Clemson University Center for Human Genetics invite applications for a postdoctoral fellow to support an NIH grant, Genetics of Cocaine and Methamphetamine Sensitivity in Drosophila. The Center is housed in Self Regional Hall on the campus of the Greenwood Genetic Center and provides state-of-the-art facilities for genomic and systems genetic research.

Illegal use of psychostimulants, such as cocaine and methamphetamine, presents a worldwide health problem. Illicit drug use alone accounts for $181 billion in health care, productivity loss, crime, incarceration, and drug enforcement. However, little information is available regarding genetic susceptibility to the effects of these drugs in human populations. Drosophila melanogaster presents a powerful model system to study the genetic underpinnings of drug susceptibility, since both the genetic background and environment, including exposure to drugs, can be controlled precisely. Many effects of psychostimulants on people are replicated in flies, including suppression of sleep, arousal, suppression of food intake, and locomotor effects; and 70% of fly genes have human orthologs. The successful candidate will assess the role of variation in brain morphology on naïve and experience-dependent drug consumption, and perform bulk and single cell RNA and ATAC sequencing of Drosophila Genetic Reference Panel lines that are genetically divergent for drug consumption behaviors.

Applicants with expertise in any aspect of genetics/genomics, including molecular, developmental, behavioral, quantitative or statistical genetics, and aptitude for analyses of large data sets are encouraged to apply. Salaries are commensurate with NIH postdoctoral pay scale and postdoctoral fellows will receive an annual $15,000 discretionary research supplement along with ample opportunities to travel to conferences both nationally and internationally.


Qualifications:

The successful candidate will possess a PhD in Genetics and assess the role of variation in brain morphology on naïve and experience-dependent drug consumption, and perform bulk and single cell RNA and ATAC sequencing of Drosophila Genetic Reference Panel lines that are genetically divergent for drug consumption behaviors.

Applicants with expertise in any aspect of genetics/genomics, including molecular, developmental, behavioral, quantitative or statistical genetics, and aptitude for analyses of large data sets are encouraged to apply.


Application Instructions:

To apply, please submit a curriculum vitae with list of publications and the names of three references to Interfolio at: http://apply.interfolio.com/62002 . The position will remain open until filled.

Inquiries regarding the position should be addressed to Dr. Trudy F. C. Mackay, Self Family Endowed Professor and Director of the Center for Human Genetics, Clemson University, Self Regional Hall, 114 Gregor Mendel Circle, Greenwood, SC 29646 ([email protected]).

 

 

 

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Job No:
Posted: 4/8/2019
Application Due: 12/10/2019
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