DescriptionUniversity of Colorado – School of MedicinePost-Doctoral Fellow
TheUniversity of Colorado Denver | Anschutz Medical Campus is a public researchuniversity serving more than 18,000 students. We award nearly 4,000 degreeseach year, including more graduate and professional degrees than any otherColorado institution. With our solid academic reputation, award-winning facultyand renowned researchers, we offer more than 140 highly rated degree programsthrough 13 schools and colleges. The university receives over $400 million inresearch awards each year. In addition to the wide array of health-relatedprograms and facilities offered at CU Anschutz in Aurora, Colo. a significantnumber of undergraduate and graduate degree programs are taught at CU Denver,our comprehensive campus in the heart of downtown Denver—one of America’s mostvibrant urban centers. CU Denver is located steps from the Denver Center forPerforming Arts and the LoDo District affording our students, faculty and staffaccess to a broad array of academic, professional, community, recreational and culturaloutlets
Anational leader in health care and life sciences, CU Anschutz is the onlycomprehensive academic health sciences center in Colorado and the largest inthe Rocky Mountain region. Located in Aurora, Colo., it is one of the newesteducation, research and patient care facilities in the world. With six schoolsand colleges, CU Anschutz trains the health sciences workforce of the future byblending education, research and clinical care all in one place. This strategiccollaboration among diverse health care fields allows knowledge to traveldirectly from the research bench to the patient’s bedside. ReadCU Anschutz Quick Facts here
TheDepartment of Pathology has Postdoctoral fellow position available for highlymotivated candidates with a fresh PhD in Biochemistry, Molecular/ cell Biology,Cancer Biology or Neuroscience to join the the Department of Pathology, Schoolof Medicine, University of Colorado Anschutz Medical Campus.
Thisposition provides a unique opportunity to be part of an enthusiastic researchteam working towards increasing survival for brain metastasis patients boththrough basic and translational research. Our goal is to unveil the mechanismsthat allow cancer cells to spread to and colonize the brain and to discovernovel therapeutic strategies for brain metastases
- Defining howhormones regulate early extravasation and blood-brain-barrier dysfunctionduring metastasis.
- Defining how estrogenaffects microglia recruitment and polarization during brain metastaticcolonization.
- Define howbreast cancer cells adapt to the brain microenvironment and become resistant totargeted therapies.
- Identifying novel targetable markers forestablished brain metastases in breast cancer.
Toachieve our goal, we use a variety of neuroscience, molecular biology, cell andtissue imaging and in vivo modeling of metastasis. We work in closecollaboration with neurosurgeons and oncologists and use human-derived samplesto help the translation of our basic research into real-life treatments.
- Organization andcommunication. While team members are working independently we recognize it is ourjoined efforts that make us successful. We encourage open and honestcommunication and collaboration between team members.
- Creativethinkers, innovators, and problem solvers.
- People who cansee the “big picture” while being meticulous about details.
Specificjob description/duties include but are not limited to:
- Performingpre clinical studies with brain metastasis patient-derived cancer cells andcancer cell lines. Isolation and characterization of cancer and brain cellpopulations from clinical samples and mice, tissue labeling and imaging. Invitro cell culture and cell-based assays, standard molecular and biochemistry techniques.
- Contributeto maintain a high standard of quality and cleanliness in the lab, maintainrelevant databases updated.
- Maintainupdated notebooks and relevant databases, present progress reports weekly.
- Criticallythink and carry on experiments from design to data interpretation (this is amust).
- Ableto work independently after initial training with minimum supervision
- Writegrants and manuscripts, and present at scientific conferences.
PhD in Biochemistry,Molecular/ cell Biology, Cancer Biology or Neuroscience
Theideal candidate will:
- havenatural curiosity and critical thinking skills
- be highlymotivated to advance in this field
- be self - drivenand forward focused
- have a passionfor innovative, transformational research
- be a master oforganization and multi-tasking
- have the utmostrespect for the research that we do, particularly when handling human andanimal tissue
- be internallyself-aware, able to communicate freely both discoveries and challenges
Salary and Benefits:
Salary is commensurate with skills and experience. TheUniversity of Colorado offers a full benefits package. Information onUniversity benefits programs, including eligibility, is located at Employee Services.
The University of Colorado Denver is dedicated to ensuring asafe and secure environment for our faculty, staff, students and visitors. Toassist in achieving that goal, we conduct background investigations for allprospective employees.
The University of Colorado strongly supports the principleof diversity. We encourage applications from women, ethnic minorities, personswith disabilities and all veterans. The University of Colorado is committed todiversity and equality in education and employment.
The Immigration Reform and Control Act requires thatverification of employment eligibility be documented for all new employees bythe end of the third day of work. Alternative formats of this ad are availableupon request for persons with disabilities.
Job Category: Faculty
Primary Location: Aurora
Posting Date: Sep 21, 2017
Unposting Date: Ongoing