Post-Doctoral Scholar - Metabolomics/Proteomics (Leggas lab)

Job description

Posting Details

Posting Details

Job TitlePost-Doctoral Scholar - Metabolomics/Proteomics (Leggas lab)Requisition NumberDU05048Department Name7K300:PHARMACEUTICAL SCIENCESWork LocationLexington, KYSalary Rangeminimum - $47,476Type of PositionTemporaryPosition Time Status Full-TimeRequired Education

PhD or equivalent degree in biomedical sciences

Required Related Experience

Experience working both independently and under direction is also critical. Ideally, the candidate should have experience with quantitative liquid chromatography-mass spectrometry applied to complex biological specimens. Comfort in working with primary human biospecimens is a necessity. Demonstrated capability in bioinformatics, demonstrated scientific writing skills, and successful ability to pursue funding will be considered favorably. Research around targeted and untargeted metabolomics is a core responsibility of this position. Individuals with an interest in integrating multi-omic data sets are especially encouraged to apply.

Required License/Registration/Certification


Physical Requirements

Sitting for long periods of time.
Lifting, pushing, pulling up to 20 lbs.
Standing for long periods of time


Monday – Friday. Some nights and weekends may be required.

Job Summary

We are recruiting a postdoctoral fellow in Mass Spectrometry based -omics (metabolomics/lipidomics/proteomics) at the University of Kentucky Department of Pharmaceutical Sciences. The fellow will participate in an exciting clinical project that seeks to understand homeostatic deregulation in infants who are born physically dependent on opioids. The ultimate goal of the project is to develop biomarkers that can be used to guide therapeutic decisions in this population and potentially extend the results in the adult setting. This is a NIDA funded project that will draw on serial biospecimens from 200 infants who are receiving treatment for neonatal abstinence syndrome or neonatal opioid withdrawal syndrome (NAS/NOWS). The fellow will initially implement untargeted metabolomics approaches and will build upon those data with additional -omics platforms such as lipidomics and proteomics. Data integration with ongoing genetic, epigenetic and microbiome analyses are also possible.

The position seeks a trainee whose primary expertise are in Mass Spectrometry Metabolomics but are willing to extend their skillset and incorporate other -omics approaches. The post-doc will perform sample preparation, LC-MS instrument maintenance and operation to acquire highly reproducible data and metabolite identification. They will contribute to study design and analytical method development and apply cutting-edge bioinformatic and statistical analysis.

Depending on the fellow’s expertise, and as the project evolves, interfacing with campus centers or outside collaborators may be required to gain additional expertise in lipidomics and proteomics platforms. The post-doc is expected to work independently and will interface with the PI a senior graduate student and collaborators.

This position is available immediately. Please submit the following:
1. Cover letter highlighting interest in the position and relevant qualifications
2. Curriculum vitae
3. Copy of the transcript (unofficial)
4. Copy of relevant publications (specific request 1)
5. Name and contact information of three references (specific request 2)

Skills / Knowledge / Abilities

-Work in a collaborative and interdisciplinary environment.
-Maintain excellent lab citizenship.
-Develop standard operating procedures for junior staff and students.
-Design, conduct, and communicate technically complex experiments.
-Develop liquid chromatography-high resolution mass spectrometry methods for detection of molecules of interest and adhere to standard practices in the field.
-Contribute to the intellectual environment of the laboratory and department through presentations.

Does this position have supervisory responsibilities? NoPreferred Education/ExperienceDeadline to ApplyUniversity Community of Inclusion

The University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus.

As an Equal Opportunity Employer, we strongly encourage veterans, individuals with disabilities, women, and all minorities to consider our employment opportunities.

Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.

Posting Specific Questions

Required fields are indicated with an asterisk (*).

    Applicant DocumentsRequired Documents
    1. Curriculum Vita
    2. Cover Letter
    3. Academic Transcript
    4. Specific Request 1
    5. Specific Request 2
    Optional Documents




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      Job No:
      Posted: 2/25/2019
      Application Due: 8/16/2019
      Work Type: