UNIV - Postdoctoral Scholar - Biochemistry & Molecular Biology

Location
Charleston, SC
Posted
Jan 07, 2019
Faculty Jobs
Arts & Humanities
Position Type
Postdoc
Institution Type
Four-Year Institution
UNIV - Postdoctoral Scholar - Biochemistry & Molecular Biology Job no: 510891
Entity: MUSC University
Department: COLLEGE OF MEDICINE - COM-Biochemistry & Molecular
Sub Department: UNIV-2211000-Biochemistry & Molecular Biology
Work type: Full-Time
Employee Type: UNIV - Post Doc
Location: Charleston, SC-Main Campus
Categories: Post Doctoral Scholar
Pay scale: UNIV-Band 0: Commensurate with experience.

Job Duties:10Participation in shared lab duties, i.e. reagent maintenance and inventory, general equipment/lab maintenance, data management.Essential15Prepare cell culture samples by transfection and/or lentivirus.Essential20Cloning and subcloning of mouse and human genes using standard molecular biology techniques, DNA and RNA purification.Essential20Maintain mouse colony specific to project including genotyping, perform monitoring, dissections, and histology.Essential25Biological assays, westerns, RT-qPCR, DNA isolation, microscopy.Essential3Keep the lab organized and clean.Essential7Scholarly activities- including manuscript preparation, poster and oral presentations at conferences.Essential

Job summary: Dr. Delaney, PhD, has an opening in his laboratory for a self-motivated and independent Postdoctoral Scholar.

Delaney Lab projects are centered on investigating how chromosomal copy number changes alter cell biology, particularly in the context of cancer using mouse and ovarian cancer cell lines as model systems. We have developed bioinformatic algorithms to evaluate copy number alterations at an integrative and systems level, and use the informatics to prioritize which genes to study in a biological context. Our strongest success in ovarian cancer has been in evaluating the suppression of autophagy. We explore the interactions of autophagy and genomic instability, as well as how to therapeutically take advantage of altered autophagy.

The ideal candidate has previously used CRISPR-Cas9 to introduce sequence alterations by homologous recombination or other mechanisms (more than simple indel deletion), however this is not required if the candidate has demonstrated productivity as evidenced by peer-reviewed publications.

Opportunities to learn and use R for data science are also available and encouraged.

Please visit http://www.delaneylab.com/ to find out more about the lab and the research.

The ideal candidate is very well organized and able to create documentation in Word, Excel, and Google Docs. The Postdoctoral Scholar must be able to work well in a team setting, including the mentoring of undergraduates and colleagues. Previous experience with autophagy and/or metabolic assays, cell culture, and bacterial plasmid preps is desired but not required.

The candidate must be willing to work with mice and lentivirus in an oncology context.

The candidate is expected to work hard while in the laboratory, however Dr. Delaney’s lab culture fosters work-life balance.

EEO Statement: MUSC is an equal opportunity employer and makes employment decisions without regard to age, race, gender, gender identity, disability or protected veteran status.

Payscale Salary Range: UNIV-Band 0: Commensurate with experience.

FLSA: Salaried

Minimum Experience and Training Requirements: The ideal candidate has previously used CRISPR-Cas9 to introduce sequence alterations by homologous recombination or other mechanisms (more than simple indel deletion), however this is not required if the candidate has demonstrated productivity as evidenced by peer-reviewed publications.

Opportunities to learn and use R for data science are also available and encouraged.

The ideal candidate is very well organized and able to create documentation in Word, Excel, and Google Docs. The Postdoctoral Scholar must be able to work well in a team setting, including the mentoring of undergraduates and colleagues. Previous experience with autophagy and/or metabolic assays, cell culture, and bacterial plasmid preps is desired but not required.

The candidate must be willing to work with mice and lentivirus in an oncology context.

The candidate is expected to work hard while in the laboratory, however Dr. Delaney’s lab culture fosters work-life balance.

Physical Requirements: Ability to perform job functions in an upright position. (Frequent) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb, using step stool. (Infrequent) Ability to work in temperature extremes (32? F to 100? F) when required due to assignments in cold rooms and/or foreign countries. (Infrequent) Ability to work in confined/cramped spaces. (Continuous) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Frequent) Ability to fully use both legs. (Frequent) Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions. (Frequent) Ability to maintain good olfactory sensory function/distinction. (Continuous) Ability to lift materials up to 20 lbs., unassisted. (Infrequent) Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted. (Frequent) Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted. (Infrequent) Ability to lift file boxes, from floor level to counter tops, unassisted. (Frequent) Ability to push/ Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted. (Infrequent) Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted. (Infrequent) Ability to push/pull file boxes from one location to another at floor level. (Frequent) Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted. (Frequent) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to maintain 20/20 vision, corrected. (Continuous) Ability to match or discriminate between colors, normally. (Continuous) Ability to hear and recognize various alarms emitting from work area systems. (Continuous) Ability to hear and/or understand conversations. (Continuous) Ability to work in a darkroom for processing film, etc. (Continuous) Ability to be qualified physically for respirator use, initially and annually. (Continuous)


Opening date: 28 Nov 2018 Eastern Standard Time
Applications close: 27 Nov 2019 5:00 PM Eastern Standard Time

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