Research Specialist 2
Hyde Park Campus
About the Unit
The Section of Transplantation is built on a strong history of surgical excellence, including the first-ever animal organ transplant in 1904. Over the years, the section has gone on to achieve many more ‘firsts,' including the first successful living-donor liver transplant and the first heart-liver-kidney transplant in the world. Today, the University of Chicago Medicine is home to one of the busiest organ transplant centers in the nation and offers more transplant options than any other program in Illinois. What our surgeons can achieve in the operating room would not be possible without the ongoing work that is done in our laboratories, and this is especially true in the Section of Transplantation. Our researchers are well known for their basic science research in transplantation tolerance and clinical trial work around islet cell transplantation for diabetes.
Under limited supervision of the PI, Section Administrator and Laboratory Manager, provides technical support to the Pancreatic Islet and Regulatory T Cell Transplantation Research Lab at the Department of Surgery by performing moderately complex laboratory techniques and teaching basic laboratory techniques. May oversee daily operations of the laboratory. Completes and maintains accurate records of performed duties. Follows and may assist in developing and improvements of laboratory standard operating procedures. Assists in development of laboratory procedures to ensure accurate collection and analysis of laboratory samples or research data. Utilizes research methods requiring a high degree of proficiency to achieve established research objectives. Evaluates existing methods and objectives.
70% Facilitate/contribute to the clinical activities of the laboratory:
- Is responsible for Current Good Manufacturing Practicies (cGMP) facility and reagent preparation for the human pancreatic islet isolation
- Assists during human islet isolation process
- Prepares supplies in the cGMP facility and routinely checks supplies inventory
- Performs quality control and release criteria tests of final islet product in compliance with internal Standard Operating Procedures (SOPs), lab policies and applicable regulations
- Assists in equipment maintenance and troubleshooting
- Assists in materials preparation, washing and sterilization
- Assists in drafting and improvements of SOPs and other laboratory documentation
30% Facilitate/contribute to research activities of the laboratory:
- Contributes to the research projects/programs being conducted in the laboratory with specific skills from an extensive, demonstrated background and technical expertise in biological science and biochemistry.
- Is responsible for laboratory housekeeping, including equipment maintenance and laboratory inventory.
- Helps in data analysis, description of laboratory materials and methods to manuscripts and grant proposal, assists in manuscripts and grant proposals submission processes.
- Performs routine library work, including finding literature and copying articles.
- Organizes data into professional format, summarizes results, and presents data to PI and in lab meetings.
- Effectively communicates, coordinates, and troubleshoots team-based research efforts through participation in laboratory and research meetings.
- Maintains clear, accurate, complete, and timely reports of experiments.
- Maintain records to ensure compliance with biosafety, radiation safety, animal protocols, compliance reports, instrument maintenance, and supply orders.
- Notify PI of any potential violations of regulations.
- Supervises and trains trainees and other lab personnel in research techniques, instruments, laboratory methods, procedures, and safety.
- Helps monitor compliance with institutional, state, and federal regulatory policies, procedures, directives, and mandates.
- Specifically maintains records for compliance (purchasing, compliance with institutional protocols, etc).
- Participates in research with laboratory animals.
- Other duties as assigned.
- Knowledge in relevant the biological sciences or chemistry required
- Basic laboratory skills: pipetting, buffer/reagents preparation, basic laboratory equipment use required
- Basic skills in mammalian cell culture procedures required
- Basic knowledge of aseptic techniques required
- Knowledge of regulatory policies and procedures required
- Problem-solving skills required
- Attention to detail required
- Organizational skills required
- Ability to learn new research techniques or methods required
- Ability to work independently and as part of a team required
- Knowledge of Microsoft Office package required
- Analytical skills required
- Verbal and written communication skills required
- Ability to train others required
- Deep knowledge of aseptic techniques preferred
- Knowledge of cGMP/cGLP regulations related to the laboratory work preferred
- Knowledge of sterilization techniques preferred
- Experience in laboratory inventory systems preferred
- Experience in working in the clean room environment preferred
- Familiarity with grant preparation preferred
- Knowledge of statistical analysis and statistical software preferred
Education, Experience or Certifications:
- Bachelor's Degree in the field of biological sciences required
- Advanced degree in the field of biological sciences preferred
- A minimum of 3 years of laboratory experience in the field of cell biology, cell therapy or other related field required
- Experience in laboratory work accordingly to current Good Manufacturing Practices and laboratory Practices (cGMP/cGLP) regulations preferred
- Experience in laboratory rodents handling and aseptic techniques in rodent survival surgery preferred
- Cover Letter
- Contact information for at least 3 supervisory references
Note: When applying, all required documents MUST be uploaded under the Resume/CV section of the application.
Depends on Qualifications
Scheduled Weekly Hours
Job is Exempt?
Drug Test Required?
Does this position require incumbent to operate a vehicle on the job?
Health Screen Required?
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