Hyde Park Campus
2012501 BSD PATH - Molecular Pathology
About the Unit
The Division of Genomic and Molecular Pathology is seeking a Senior Bioinformatician to help support the personalized oncology services of the Clinical Genomics Laboratory in the Division of Genomic and Molecular Pathology. The Division is looking for individuals who will contribute their skills in a fast-paced cutting edge environment and will leverage state-of-the-art software and data analysis systems to deliver innovative and exciting solutions to support clinical care and translational investigation. Duties will include day-to-day clinical data management, next generation sequencing (NGS) assay development and validation efforts as well as involvement in a variety of NGS-related translational research projects. The individual will also assist in preparing manuscripts or grants. The individual will provide timely support to projects assigned to them, and participate in Bioinformatics team efforts. The Division is highly collaborative, and the individual filling this position will have ample opportunity for research collaboration and publications in both clinical and translational genomics.
The individual will be responsible for design, implementation and operation of application-oriented bioinformatics pipelines to process next generation sequencing data from clinical NGS diagnostics and from a variety of translational genomics studies. The individual will also develop novel tools and software as needed to achieve proper pipeline and assay performance. Post-processing statistical analysis of results and biological interpretation of data is also required.
- Ensure timely processing and review of clinical NGS data from patient samples processed in the Clinical Genomics Laboratory.
- Implementation of novel software and pipelines to facilitate assay development and translational science studies.
- Analysis, display and interpretation of genomic data to support clinical development, including creation of validation summary documentation in accordance with Clinical Laboratory Improvement Amendments (CLIA) guidelines.
- Ensuring proper maintance, organization, and backup of clinical laboratory data on on-site high performance computing cluster systems.
- Participation in translational research studies within the Clinical Genomics Laboratory, in collaboration with GMP faculty and other investigators. Includes experimental design, pipeline development, novel software engineering, custom data analysis, data integration, authorship and presentation.
- Assisting with pathology resident and fellow education in bioinformatics.
- Strong knowledge of next generation sequencing methodology and data analysis.
- Knowledge in bioinformatics or computational biology required, including statistical analysis and biological interpretation of data.
- Skills and experience with next generation sequencing data types and customary analysis software is required, as well as knowledge and skills related to analysis pipeline development.
- Prior experience working with large-scale datasets using high performance computing environment is a plus.
- Software development skills using Python, R, Bash, MySQL and other systems.
Education, Experience or Certifications:
- Masters (minimal level) or PhD in Bioinformatics or Computational Biology or equivalent, required.
- 4 years experience in computer programming; required, including proficiency in Python, R, Bash, MySQL.
- 3 years experience in scientific data processing and bioinformatics; required.
- 2 years experience performing analysis of next generation sequencing data; required.
Technical Knowledge or Skills:
- Strong computing skills and Linux experience, including software development experience in multiple programming languages, including Python and R.
- Next generation sequencing bioinformatics knowledge, preferentially with previous cancer and clinical laboratory experience.
- Scientific data analysis and presentation skills.
- Cover Letter
- Reference Contact Information
NOTE: When applying, all required documents MUST be uploaded under the Resume/CV section of the application
Depends on Qualifications
Scheduled Weekly Hours
Job is Exempt?
Drug Test Required?
Does this position require incumbent to operate a vehicle on the job?
Health Screen Required?
Remove from Posting On or Before
The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.
Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.
The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.
The University of Chicago is an urban research university that has driven new ways of thinking since 1890. Our commitment to free and open inquiry draws inspired scholars to our global campuses, where ideas are born that challenge and change the world.
We empower individuals to challenge conventional thinking in pursuit of original ideas. Students in the College develop critical, analytic, and writing skills in our rigorous, interdisciplinary core curriculum. Through graduate programs, students test their ideas with UChicago scholars, and become the next generation of leaders in academia, industry, nonprofits, and government.
To learn more about the university click here http://www.uchicago.edu/