Hyde Park Campus
2012501 BSD PATH - Molecular Pathology
About the Unit
The Principal Bioinformatician position within the Division of Genomic and Molecular Pathology (GMP) at the University of Chicago is a technical and scientific leadership position with critical roles in the provision of next generation sequencing (NGS) clinical diagnostic services and translational genomics research. The Principal Bioinformatician leads a team of bioinformatics professionals in order to support development and validation of new NGS testing methodologies for personalized oncology as well as perform collaborative and independent translational genomics research projects, frequently involving creation of novel analysis software and other analytical and information systems. Other key responsibilities include performance and oversight of clinical bioinformatics practice in accordance with CLIA regulations, mentorship of team members, and developing a vision to prepare for the future informatics and analytical needs of the division. The GMP division's Clinical Genomics Laboratory is one of the most advanced academic NGS oncology clinical diagnostics labs in the United States, providing many opportunities for both clinical development and scientific advancement. It is the expectation that the individual filling this role will help to guide the future directions of the division and the department with respect to informatics science.
Responsible for keeping current with relevant scientific or medical journals and recommending potential solutions based on the latest technical developments. An active leader in the bioinformatics community who fosters innovation and creativity. Assembles and manages an effective bioinformatics support team. Responsible for project timelines, documentation, and staff management.
- Provides leadership and oversight on the delivery of the bioinformatics vision and strategy.
- Establish the genomics and informatics direction of the division in concert with other leaders.
- Create and maintain NGS analysis systems in accordance with the highest clinical standards.
- Provide direct supervision and mentoring of bioinformatics staff.
- Foster a continuous learning environment supporting training opportunities.
- Cultivate an inclusive, innovative and creative culture.
- Lead bioinformatics projects to ensure implementation in a timely and efficient manner with compliant, appropriate documentation.
- Build collaborative relationships across the bioinformatics community, to create novel approaches to optimize upstream and downstream analysis and interpretation of data.
- Design the analysis of data resulting in a better understanding of human genetic variation and the association of medical information to uncover gene-disease links and new targets.
- Ensure the quality of the analysis processes and analysis pipelines.
- Provide guidance and oversight on the development of new software applications or the customization of existing applications to meet specific scientific project needs.
- Communicate results with other scientists; refine analysis based on feedback, and contribute to the design, plan and follow-up of experiments to validate in-silico discovery.
- Engage in impactful collaborative and independent translational genomics research.
- Prepare clear, concise and easy-to-understand presentations and documentation for collaborators, senior management and regulatory agencies.
- Organize research collaborations and provide direct high-level technical support for research projects and other relevant audience.
- Other duties as assigned.
- Ability to lead teams of biologists, bioinformaticians and biostatisticians to provide hands-on technical expertise required.
- Ability to foster a creative and innovative culture required.
- Ability to coach, motivate and inspire others required.
Education, Experience, or Certifications:
- Master's degree in Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related field required.
- PhD in Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related field preferred.
- Minimum of five years of hands-on experience in the field of next generation sequencing bioinformatics required.
- Three years of direct clinical laboratory NGS bioinformatics experience strongly preferred.
- Fluency in Python, R and BASH strongly preferred.
- Experience supervising people and projects strongly preferred.
- Project management experience required.
- Resume or CVs
NOTE: When applying, all required documents MUST be uploaded under the Resume/CV section of the application
Depends on Qualifications
Scheduled Weekly Hours
Job is Exempt?
Drug Test Required?
Does this position require incumbent to operate a vehicle on the job?
Health Screen Required?
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