Basic Life Res Scientist
The Research Scientist will be involved directly in the execution, and frequently the design of research activities related to developing more robust recombinant AAV vectors for gene therapy. The candidate will support the PI with designing experiments constituting a phase of a research project for which precedents are few.
The candidate will support the preparation of various in vitro and in vivo study protocols, proposals, progress, and final reports as well as be likely co-author on reports for publication or professional presentation with the work being reviewed by the PI or faculty. S/he will present ongoing work and findings to colleagues in internal and external research settings and complete project-related administrative and budgetary responsibilities of a limited scope as needed. It is expected that the Research Scientist also help oversee the guidance of postdoctoral scholars, graduate and undergraduate students in the laboratory.
Duties include: Design research approaches to modify rAAV vectors to enhance their properties. Original research and problem solving, and writing up for publication.
Develop new approaches for analyzing the AAV variants that include newer methods of high throughtput DNA sequencing.
Participate in complex in vitro and in vivo animal experiments, and maintain detailed records of experiments and outcomes; analyze and interpret research data resulting from original procedures and methods.
Assist with new research proposals and applications for funding and grants.
Prepare periodic progress reports or written reports on all phases of the research project.
Give presentations in weekly laboratory meetings
Contribute substantively to the preparation of papers for publication, especially in the results section. Present ongoing work and findings to colleagues at academic conferences.
Perform ongoing literature review to remain current with new procedures and related research to AAV vector biology and translational applications
Produce AAV vectors for collaborations within and outside the laboratory Required:
An MD, PhD or equivalent degree in biomedical field and at least five years of molecular biology research experience.
Comprehensive understanding of scientific principles preference is for experience in rAAV biology, DNA shuffling technologies and/or general molecular virology.
Technical competence in basic virology and vectorology, molecular biology and high-throughput sequencing.
Strong molecular and cell biology techniques, as well as significant mouse experimental studies.
Strong analytical skills, excellent judgment, and demonstrated excellence, innovation and productivity in research.
Ability to work under deadlines with general guidance is essential.
Excellent organizational skills and demonstrated ability to complete detailed work accurately and record thoroughly.
Developed project management skills.
Able to work independently and function effectively as part of a team of physicians, students, postdoctoral fellows, and laboratory and animal technicians and staff.
Potential to train new comers to the laboratory.
Optimally 10+ years of experience in molecular and cell biology (including training period OK)
5 years or more training in AAV biology and/or DNA shuffling technologies.
“Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.”
Location: School of Medicine, California, United States
To be considered for this position please visit our web site and apply on line at the following link: stanfordcareers.stanford.edu
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.
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