Postdoctoral Scientist, Wu lab
I. DEPARTMENT INFORMATION
Job Description Summary:
Research and discovery is at the core of the mission of GW School of Medicine and Health Sciences. By advancing translation of research and increasing interdisciplinary collaboration in key areas of strength, SMHS researchers are identifying novel approaches to address the world’s most devastating health issues.
Dr. Wu’s lab in the Department of Medicine focuses on two epigenetic modulators and members of the AT-rich interaction domain family, ARID4A and ARID4B. Epigenetics plays an important role in human health and disease. Disruption of epigenetic modifications leads to dysregulation of gene function without altering the DNA sequence per se. A major challenge in understanding the importance of epigenetics in human health and diseases is to identify the specific epigenetic factors and the signaling involved.
Currently, we are investigating the role of ARID4A and ARID4B in development and cancer disease using state-of-the-art conditional knockout mouse models and genomic and proteomic approach. We also study the role of ARID4B in cancer stem cells that have been suggested as the major cause for therapy resistance and the driving force behind cancer metastasis and relapse. To investigate whether and how ARID4B drive cancer development, we evalute the underlying molecular mechanisms by which ARID4B promotes therapy resistance and aggressive cancer.
Dr. Wu’s lab in the Department of Medicine has an opening for a Postdoctoral Scientist.
-culture and transfection of mammial cells
-collection of samples for reporter gene assays
-western blooting to analyze protein expression
-cancer cell migration and invasion assays -human cancer xenogrant experiments using SCID/NOD mice.
-other duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.
This post-doc scientist is also required to work with genetically modified mice and in a BSL2 laboratory setting.Minimum Qualifications:
Qualified candidates will hold a PhD in a related discipline. Degree must be conferred by the start date of the positionAdditional Required Licenses/Certifications/Posting Specific Minimum Qualifications: Preferred Qualifications:
Ph.D. degree, with experience in molecular and cellular biology.
I. POSITION INFORMATION
Campus Location: Foggy Bottom, Washington, D.C. College/School/Department: School of Medicine and Health Sciences (SMHS) Family Research and Labs Sub-Family Laboratory Research Stream Individual Contributor Level Level 3 Full-Time/Part-Time: Full-Time Hours Per Week: 40 Work Schedule: Monday through Friday, 8:30 to 5:30 Position Designation: Essential: Employees who perform functions that have been deemed essential to maintaining business or academic operations. Employees are generally expected to work from home during an event and may be asked to physically report to work. Telework: Required Background Check Criminal History Screening, Education/Degree/Certifications Verification, Social Security Number Trace, and Sex Offender Registry Search Special Instructions to Applicants: Internal Applicants Only? No Posting Number: R000453 Job Open Date: 01/16/2018 Job Close Date: If temporary, grant funded or limited term appointment, position funded until: Background Screening Successful Completion of a Background Screening will be required as a condition of hire. EEO Statement:
The university is an Equal Employment Opportunity/Affirmative Action employer that does not unlawfully discriminate in any of its programs or activities on the basis of race, color, religion, sex, national origin, age, disability, veteran status, sexual orientation, gender identity or expression, or on any other basis prohibited by applicable law.
Posting Specific Questions
Required fields are indicated with an asterisk (*).
- Cover Letter
- Curriculum Vitae
- Names and Contact Information for References
- Letter of Recommendation 1
- Letter of Recommendation 2
- Letter of Recommendation 3
- List of Publications