Research Associate

Job description

Working Title: Research Associate

Position Type: Professional Research Staff

Department: Department of Anesthesiology

Location: Charlottesville

Posting Date: 05-04-2017

Posting Summary:
Dr. Zhiyi Zuo, M.D., Ph.D. (151 PubMed citations from 2002-2017) and Dr. Robert Thiele, MD (59 PubMed citations from 2008-2017), a NIH K-08 awardee run an active lab focussed on organ protection and preconditioning in stroke and sepsis in the Department of Anesthesiology at the University of Virginia. They are currently seeking a Post-Doc Research Associate to focus on organ protection and developing greater understanding of sub cellular energetics.

The fellow will work alongside Dr. Thiele, under the guidance of Dr. Zuo, to better understand how cells and organs respond to hypoxic and inflammatory insults. Traditional laboratory techniques (e.g. analysis of HIF-1, iNOS by Western blot, ADP:ATP ratios) will be combined with novel technology (near infrared spectroscopy) to determine whether or not the metabolic shutdown that accompanies stress is maladaptive or pro-survival, better understand the balance of O2 availability and ROS/RNS production (and subsequent oxidative stress), assess the impact of preconditioning and HIF-1 down regulation on tolerance for inflammatory stress.

The applicant must have a PhD or MD by the start date and have extensive experience in standard biochemical procedures (Western blot, ELISA, ADP:ATP ratio, mRNA isolation for qPCR) as well as working with cell culture and rodents.

In addition to Drs. Zuo and Thiele, the laboratory employs a full-time Ph.D. researcher in biomedical engineering to assist with technical (near infrared spectroscopy) and computational work. The Zuo laboratory has had consistent academic output for the last fifteen years and continuous NIH funding since 2003.

To apply, please visit: and search for Posting Number 0620895. Create a candidate profile and submit a CV, Cover letter and contact for 3 references.

For questions regarding the application process, please contact Greg Haskins via email at [email protected] or via telephone at (434) 924-2963

The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.

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Job No:
Posted: 9/11/2018
Application Due: 11/10/2018
Work Type: