Working Title: Laboratory Specialist
Position Type: University Operational and Administrative Staff
Department: Department of Pediatrics
Posting Date: 09-10-2018
The Department of Pediatrics at the University of Virginia is seeking a Laboratory Specialist. The position carries out research studies and assists in experiments for the laboratory of Dr. Daniel "Trey" Lee, MD, a pioneer in the use of Chimeric Antigen Receptor (CAR) T cells for the treatment of pediatric malignancies (PMID: 25319501). The focus of the Lee Lab is to develop and rapidly translate new CAR T cell therapies to the clinic through the initiation of investigator-initiated clinical trials at UVA. The incumbent will assist in the establishment and management of the laboratory and perform experiments supporting the goals of the lab with the supervision of the PI and other staff. Research in the lab utilizes human patient and normal donor samples in addition to using small animal models of disease (required) and tumor cell lines.
The incumbent also attends weekly meetings with the Principal Investigator to discuss experimental results, conducts literature searches, and presents results in lab meetings. The incumbent works under supervision, independently and ethically, documents all research data appropriately, and assists other members of the lab.
Qualified candidates must have either 1) a Bachelor's degree in life sciences, biomedical engineering or a related interdisciplinary field with a minimum of 2-years' experience in a laboratory setting after obtaining the degree, or 2) a Master's degree in cancer biology, tumor immunology, immunology or similar discipline. The successful candidate should have experience working with cell culture, small animals including basic procedures, DNA cloning and PCR. Experience with flow cytometry is desirable, but not necessary. Proficiency in Microsoft Word, PowerPoint and Excel is required. Additional expertise in statistical and data analysis software, database software, and imaging and/or image analysis software is a plus. This position also includes support activities such as ordering supplies and reagents for the laboratory. The ideal candidate will be a highly-motivated individual with excellent organizational and communication skills.
Required Knowledge, Skills and Abilities:
1. Ability to work with cancer cell culture and transfection, with in vitro techniques such as western blot and RNA assays;
2. Ability to perform mouse experiments;
3. Ability to support lab activities such as ordering supplies and reagents for the laboratory.
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