Senior Bioinformatician

Job description

Hyde Park Campus

2012217 Medicine-Hem/Onc

About the Unit

Job Information

Job Summary:

The Senior Bioinformatician will take a lead role as the primary bioinformatics and scientific resource to support project work that solves complex problems. Works at a high technical level in all phases of data management and bioinformatics support activities. Highly complex data will be analyzed by applying sound statistical and commonly accepted bioinformatics methods on a collaborative project team. He/She will be responsible for managing and administering large experimental and clinical data, including installation, operation, and administration of IT infrastructure as well as management of accompanying administrative and regulatory responsibilities. Ensures projects are managed in a timely and efficient manner and are appropriately documented. Work will be done with an interdisciplinary team and will engage with the biomedical informatics community at large on infrastructure, workflow, and pipeline development.


  • Apply state-of-the-art computational biology and bioinformatics methods and tools to generate new or validate existing testable hypotheses from complex and large biological datasets.
  • Lead the analysis of data resulting in a better understanding of human genetic variation and the association of medical information to uncover gene-disease links and new targets.
  • Work effectively with the faculty, clinicians, researchers and experimentalists, to implement novel or adapt existing approaches to optimize upstream and downstream analysis and interpretation of biological data.
  • Integrate diverse and heterogeneous datasets, to facilitate mining statistical analysis and visualizations leading to a better understanding of disease mechanisms, and the correlation between phenotype and genotype in different research projects.
  • Instruct others in the selection and use of bioinformatics tools.
  • Lead the development of new software applications and databases, or the customization of existing applications and databases to meet specific scientific project needs.
  • Identify suitable datasets and methods to answer particular research questions.
  • Design and perform formal evaluation of informatics methods and products.
  • Perform data analyst functions that generate knowledge via data mining, visualization, or other analytics.
  • Lead and conduct validation and user acceptance testing.
  • Create novel computational approaches.
  • Design best research and development practice.
  • Stay up-to-date on new advances and developments in bioinformatics and provide on-demand bioinformatics and statistics support to various teams.
  • Lead the development of training, tools, and process documentation.
  • Other duties as assigned.

  • Advanced knowledge of research techniques or methods required.
  • Ability to train others required.
  • Knowledge of development, optimization, automation, and operations support of analysis pipelines for high dimensional data including whole-genome, whole-exome, and RNA sequencing data required.
  • Ability to employ high performance computing to solve parallelizable computer problems required.
  • Server and database administration ability required.
  • Familiarity with regulations governing management of sensitive information strongly preferred.

Additional Requirements

Education and Experience:
  • Bachelor's degree and five years of relevant experience required;


    Master's degree required and three years of relevant experience required;


    PhD in Bioinformatics, Computational Biology, Computer Science, Mathematics, or a related field required.
  • Degrees in Bioinformatics, Computational Biology, Computer Science, Mathematics or a related field preferred.
  • One year of experience in programming for bioinformatics with scripting languages such as Perl, Python, R, Java, XML, C/C++ or SQL required.
  • Experience organizing and working with big data required.
  • Experience with next generation sequencing technologies such as BWA, Novoalign, STAR, GATK, samtools, Picard or other tools required.
  • Experience and proficiency in analysis pipeline development of high throughput data required.

Required Documents:
  • Resume
  • Cover Letter

NOTE: When applying, all required documents MUST be uploaded under the Resume/CV section of the application

Benefit Eligibility

Pay Frequency

Pay Range
Depends on Qualifications

Scheduled Weekly Hours


Job is Exempt?

Drug Test Required?

Does this position require incumbent to operate a vehicle on the job?

Health Screen Required?

Posting Date

Remove from Posting On or Before

Posting Statement:

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.

Full time

About Us
The University of Chicago is an urban research university that has driven new ways of thinking since 1890. Our commitment to free and open inquiry draws inspired scholars to our global campuses, where ideas are born that challenge and change the world.

We empower individuals to challenge conventional thinking in pursuit of original ideas. Students in the College develop critical, analytic, and writing skills in our rigorous, interdisciplinary core curriculum. Through graduate programs, students test their ideas with UChicago scholars, and become the next generation of leaders in academia, industry, nonprofits, and government.

To learn more about the university click here





Diversity Profile: University



View more

Learn more on Inside Higher Ed's College Page for University

Arrow pointing right
Job No:
Posted: 9/9/2018
Application Due: 11/8/2018
Work Type: