Research Assistant 4

Job description

Job Code:  #7015

Title: Research Assistant 4

Department: Infectious Disease


Working with a high degree of independence and under general direction, coordinate major activities in relation to the study the mechanisms of immunity of influenza in order to understand why there is a decline in immune function with aging. The laboratory focuses on determining defects in the human immune system that occur with aging. The research assistant will be involved in the delivery of flu vaccine and characterization of immunology in aging populations.


  1. Provide input and recommendation to principal investigator regarding significant developments in research projects related to immunology bioassays and tissue culture methods (10%)
  2. Coordinate and supervise major activities of laboratory/ research staff as they perform immunology bioassays and tissue culture (15%)
  3. Oversee subject recruitment and manage study operation including day-to-day laboratory functions (15%)
  4. Responsible for the generation, collection, and organization of data resulting from studies of human immunology to influenza and vaccines (30%)


  1. Perform the most complex quantitative analytical procedures. Prepare written reports on the results and conclusions of the statistical analyeses and develop data dictionaries (5%)
  2. Teach or instruct others in research techniques related to human specimens with live influenza virus and other pathogens (5%)
  3. Assist in developing study and laboratory procedures, coordinate information with others as needed (5%)
  4. Co-author research projects on human immunology (5%)
  5. Determine protocols from published literature in order to determine defects in the human immune system that occur with aging (5%)
  6. Perform Routine lab maintenance including cleaning equipment and lab ware, disposal of biohazardous waste, and ordering supplies. (2%)
  7. Perform other duties as assigned. (3%)


Department: Daily contact with supervisor and lab members to maintain workflow.

University: Occasional contact with other departments to exchange information.

External: Frequent contact with VA lab members.  The employee will obtain a VA status to be able to work also in the Canaday VA lab where we have a flow cytometer for our studies.  There will also be contact with outside recruiting sites such as community nursing homes multiple times weekly during the flu-shot season.  This may involve going to the nursing home sites during recruitment times.

Students: Contact with students almost daily to maintain workflow.


May supervise research assistants and technicians.


Experience: 5 to 8 years of related experience in immunology is required.

Education/Licensing: Bachelor’s degree in science field.


  1. Extensive experience doing immunology bioassays and tissue culture methods
  2. Ability to work in BSL2 setting with live influenza virus and potentially other pathogens
  3. Ability to multi-task processing of human specimens
  4. Ability to perform and analyze multi-parameter flow cytometry
  5. Strong organizational skills
  6. Some experience working directly with recruitment and sample acquisition of research subjects would be ideal but not mandatory.
  7. Phlebotomy skills are desirable but not required.
  8. Basic computer skills for data acquisition and analysis, as well as for the development of presentations.
  9. Scientific writing for presentation and manuscript preparation
  10. Ability to operate laboratory equipment.
  11. Ability to meet consistent attendance.
  12. Ability to interact with colleagues, supervisors, and customers face to face.


The employee will be required to work with blood and clinical material from humans. Use of Universal Precautions methods is practiced at all times. This position will require the handling of live influenza.  Depending on the situation, we perform these studies in the certified Biosafety Level 2 Facility and BSL3 facilities that are adjacent to the laboratory. All special training will be provided and certification by the University as required. Radioactive material will be used on rare occasions in the laboratory.  Lastly, for fixation of specimens, low concentration paraformaldehyde is used.


In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.


CWRU offers a flexible benefits package including tuition waiver for employees and dependents; Respond in confidence, including salary history:, human resources job code #7015.




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Job No: #7015
Posted: 9/4/2018
Application Due: 10/4/2018
Work Type: