Research Associate

Job description

Working Title: Research Associate

Position Type: Professional Research Staff

Department: Department of Molecular Phys and Biological Physics

Location: Charlottesville

Posting Date: 07-11-2018

Posting Summary:
The Zimmer lab at the University of Virginia School of Medicine seeks to recruit a postdoctoral research associate to work on the mechanism of bacterial complex carbohydrate secretion. The successful candidate will perform research at the intersection of glycobiology, biochemistry, and membrane protein structural biology. Our laboratory studies the biosyntheses and secretion mechanisms of extracellular glycoconjugates, with a particular interest in bacterial O antigens and capsular polysaccharides. The project requires combining techniques from molecular biology, protein crystallography, electron microscopy, and biochemistry.

The initial focus of the project will be the optimization of expression and purification of membrane-integrated transporters and larger complexes, followed by crystallization experiments as well as electron microscopy imaging. In addition, the catalytic and transport activities of the purified components will be analyzed in vitro.

The highly motivated candidate must have a Ph.D. or equivalent, have extensive experience in cloning and protein expression and purification, and should have a basic knowledge of protein crystallography. Experience in cryo-electron microscopy would be beneficial. The ability to work independently yet collaborate well with a diverse group of scientists is essential.

If qualified, please complete a Candidate Profile by going to and search on posting number 0623616. Please attach a current CV, a cover letter stating why you are qualified for this position, and the names and contact information of three references.

The position will remain open until filled.

For additional information about the position, please contact Dr. Jochen Zimmer at [email protected]

The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans and persons with disabilities are encouraged to apply.

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Job No:
Posted: 7/12/2018
Application Due: 8/8/2018
Work Type: