Job description

Duties: The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the 'go-to' organization for public and private partners, who want to participate in the gene therapy space. Currently we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

Our Vector Core is a state-of-the-art facility which provides vector-related materials and services in support of basic and translational research worldwide, producing vectors in support of IND-enabling research, conduct GLP assays, oversee CMO's in vector production and is expanding to conduct state-of-the art process development.

Due to significant growth, the Vector Core is looking for a new, Resource Technologist A, to support production and purification efforts for pre-clinical viral vectors.

As a Resource Technologist A, you will be responsible for the production and purification of research grade AAV vectors for pre-clinical, IND-enabling Pharmacology and Toxicology studies. You will be documenting your activities on production or batch record forms for QA review.

You will work both independently and as part of a team to accomplish project goals within specified timelines. Successful candidates will have a familiarity with upstream and downstream biologics manufacturing, tissue culture, column chromatography and other purification processes.

Qualifications: BS Degree in Biochemical/Chemical Engineering, Biochemistry, Biology, or related discipline and 0 to 1 year of experience or an equivalent combination of education and experience required.
Must have experience with tissue culture, column chromatography, or TFF
Experience in upstream or downstream biologics manufacturing is a plus.
Must be an independent thinker, meticulous, detail oriented, and analytical
Must be highly motivated, have excellent organizational, communication and interpersonal skills.
Must be able to work independently and as part of a multi-disciplinary team.

Reference Number: 40-29282

Salary Grade: 024

Employment Type: Exempt

Org: DM-Gene Therapy Program

Special Requirements:

Job Family: I-Technical/Professional Research




Diversity Profile: University



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Job No:
Posted: 7/10/2018
Application Due: 9/9/2018
Work Type: