Required Qualifications: (As evidenced by an attached resume)
PhD with a concentration in developmental or cell biology or related field in hand by June 1, 2018. Ability to communicate orally and written as evidenced by presentations at national meetings and publications. Ability to design, implement, and troubleshoot experiments that localize proteins using immunohistochemical and immunofluorescence staining as well as using Western blot analysis. Experienced with light, fluorescent, and confocal microscopy and digital imaging, image processing, and statistical analysis. Ability to design and troubleshoot experiments to analyze gene expression using in situ hybridization and/or quantitative RT-PCR.
First author quality publication in field of extracellular matrix cell biology or developmental biology. Competence embedding and sectioning tissues (paraffin, cryo, and/or vibratome). Competence with mouse husbandry, euthanasia, and anesthesia procedures.
Brief Description of Duties:
The post-doctoral associate will conduct experiments focused on understanding how defects in glycosylation (cause by Pofut2 and B3glct mutations) lead to birth defects in brain (hydrocephalus), skeleton (craniofacial anomalies and acromelic chondrodysplasia), eye (anterior chamber defects), and/or cardiovascular and urogenital system during development. The primary focus will be determining whether the mutations affect protein trafficking and/or alter extracellular matrix composition/properties during organ development. The successful incumbent must have strong organizational and time management skills with exceptional attention to detail. Experience successfully working independently as well as part of a team with a collaborative approach to problem-solving. Outstanding written, verbal, and interpersonal communication skills. Ability to work with minimal supervision. Meticulous record keeping.
- Design, implement and troubleshoot experiments to localize proteins in sectioned adult and embryonic tissues
- Design, implement and troubleshoot experiments to localize and quantitate mRNA in wholemount or sectioned embryos and adult tissues.
- Compile and analyze scientific data/results. Assist PI in writing and assembly of grants and manuscripts. Participate in weekly meetings with co-PI lab and present data at relevant national meetings.
- Assist with mouse Husbandry and lab organization as needed. Assist PI in compliance with federal, local, and University guidance in safety, research, ethical, and animal welfare.
- Mentor Graduate and Undergraduate students/trainees in molecular biology and cell biology techniques.
- Other duties or projects as assigned.
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Official Job Title: Postdoctoral Associate
Job Field: Post Doctoral
Primary Location: US-NY-Stony Brook
Department/Hiring Area: Biochemistry & Cell Biology-The Research Foundation for The State University of New York at Stony Brook
Schedule: Full-time Day Shift 9am - 6pmBiochemistry & Cell Biology-The Research Foundation for The State University of New York at Stony Brook
Posting Start Date: May 11, 2018
Posting End Date: May 25, 2018, 11:59:00 PM
Salary: Commensurate with experience
Salary Grade: E89