Research Assistant 2

Job description

Position ID:  #6773

Title: Research Assistant 2

Department: Cardiology UH


Working under general supervision, the research assistant 2 will plan and carry out activities to support research in the Maiseyeu lab investigating cardiometabolic diseases, such as astherosclerosis, type 2 diabetes, and obesity; as well as cardiometabolic health. This position will be primarily responsible for coordinating research activities, supporting scientists and general lab maintenance. The research assistant 2 will also collect, verify, record, and compile data and information related to the ongoing research carried out in the lab. This positon will work with animals.


  1. Plan and carry out research and projects under general supervision. Perform standard molecular procedures and operating a variety of instruments and scientific equipment, i.e. microscopy, PCR, gel electrophoresis, biochemical assays and others. Maintain cell/ tissue cultures for experimental purposes. (20%)
  2. Analyze samples. Collect, organize and analyze data, maintain records of experiments using electronic lab notebook. Organize raw data, record results and update lab-related data folders. Supply data and results to the lab. (30%)
  3. Plan and carry out techniques/procedures in regard to maintaining animal colonies. This includes diet manipulation, drug administration, organ isolation, taking care of animals and general maintenance. May assist in developing improved techniques or procedures. (20%)
  4. Configure and operate laboratory instruments; ensure instruments are kept in working order. Maintain certain equipment facilities. (10%)
  5. Oversee inventory and order reagents and other laboratory supplies. Maintain chemical/ biological inventory in compliance with EHS. (10%)


  1. Train and oversee the work of new staff, within their own area of expertise or their own line of research work. (5%)
  2. Perform other duties as assigned to ensure contribution to research results on an ongoing basis. (5%)


Department: Daily contact with principal investigator and lab personnel to communicate results and train others within their own line of research work.

University: Occasional contact with other departments to collaborate with similar research groups.

External: Limited contact with vendors to order reagents.

Students: Daily contact with undergraduate student research assistants in the laboratory to direct the work and/or make adjustments to procedures.

Supervisory Responsibility

This position has no direct supervision of staff employees. This position may train new staff or direct work of students.


Education and Experience: Bachelor's degree and 1 to 3 years of related experience, or Associate's degree in an approved biotechnology program and 2 to 4 years of experience.


  1. Significant experience with mouse models (knowledge on atherosclerosis model preferred).
  2. Proficiency in organ isolation (including aorta and bone marrow) is required.
  3. Tissue processing for histology (cryo- and paraffin-block sectioning) and histochemical staining, including immunohistochemistry and immunofluorescence.
  4. Experience with basic molecular biology techniques (PCR, RNA isolation).
  5. Computer skills and ability to quickly learn software, databases, online applications (Google and Amazon services).
  6. Good organizational skills.
  7. Ability to meet consistent attendance.
  8. Ability to interact with colleagues, supervisors and customers face to face.
  9. Must demonstrate compliance with CWRU animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.
  10. Must demonstrate compassion for animals within CWRU facilities and dedication to the Animal Resource Center’s mission.  Must handle animals with care and respect at all times.
  11. Previous experience working with animals preferred.

Working Conditions

General laboratory environment. May have exposure to hazards. Will be working with mouse models. The employee will be working with cells, and tissues from rodents as well as various chemicals involved in the conduct of biochemical assays. There are general laboratory chemicals as well. May have repetitive motion with hands and substantial time analyzing culture dishes with cells.

Case's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.


In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.


Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.


CWRU offers a flexible benefits package including tuition waiver for employees and dependents; Respond in confidence, including salary history:, human resources job code #6773.




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Job No: 6773
Posted: 4/2/2018
Application Due: 6/1/2018
Work Type: