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BIOSTATISTICIAN III

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BIOSTATISTICIAN III
Duke Human Vaccine Institute - Admin

Biostatistician III - Job Description

About DHVI
The Duke Human Vaccine Institute (DHVI) has established a place of national and international leadership in the fight against the major infectious diseases. Our investigators understand the power and opportunity of the team approach and are poised to make major new contributions to global health challenges. Programs led by the DHVI are described below.

The Center for HIV/AIDS Vaccine Immunology (CHAVI-ID) is currently one of two implementation projects under the Global HIV Vaccine Enterprise, the other being the recently funded Collaboration for AIDS Vaccine Discovery (CAVD) by grants from the Bill and Melinda Gates Foundation. The Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI-ID) is a consortium that was established by the National Institute for Allergy and Infectious Diseases (NIAID) to undertake the immunologic research that will tackle the major scientific obstacles in the development of an effective HIV-1 vaccine. The vaccine strategy of the Duke CHAVI-ID is based on identifying and targeting novel HIV-1 vulnerabilities to B, T and NK cell immune responses and using this information to design vaccines that will induce protective immunity at the time and location of HIV-1 transmission.

The External Quality Assurance Program Oversight Laboratory (EQAPOL) is a National Institute of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID)- Division of AIDS (DAIDS) funded resource located at Duke Human Vaccine Institute's (DHVI) Immunology and Virology Quality Assessment Center (IVQAC) to support the development, implementation and oversight of external quality assurance programs that monitor laboratories involved in HIV/AIDS research and vaccine trials around the world.

Occupational Summary
The Biostatistician III will be lead statistician for the CHAVI-ID Program. This work will include, but not be limited to, managing data from multiple labs, completing data checks, analyses, and report generation within the project deadlines while working independently. The Biostatistician III will perform intermediate and advanced statistical analyses in collaboration with the Biostatistics team and Principle Investigators. It is also desirable that the candidate have experience in performing bioinformatics analysis particularly in the areas of genomics and transcriptomics. The type of bioinformatics work the candidate would perform would include programming bioinformatics pipelines and implementing novel computational biology methodologies.

Duties and Responsibilities
Responsibilities:
  • Independently design, document and prepare analysis data sets for the CHAVI-ID Program as well as prepare reports describing the statistical methodologies used along with the interpretation of the statistical analysis.
  • Learn and apply new statistical methods to the CHAVI-ID Program as needed.
  • Collaborate with CHAVI-ID program project leaders and develop analysis plans for new research questions that arise.
  • Perform data management and data review using SAS and/or R for quarterly querying of labs in the CHAVI-ID Program.
  • Perform data management, analysis data set creation or verification, as well as statistical analysis for the EQAPOL Program.
  • Provide statistical input and researches potential statistical methodologies with the Biostatistics group for application in DHVI programs.
  • Write efficient and complex programs in SAS and/or R for the creation of analysis data sets as well as statistical analyses. Research and discover new programming techniques to share with the Biostatistics team.
  • Follow all SOPs and relevant guidelines (e.g., ICH, CLSI) for statistical analyses, programming, and statistical assessment of laboratory performance.
  • Manage multiple projects and deadlines, as well as provide solid estimates of statistical effort required for a research project. Communicate potential project issues with the lead researcher or Biostatistics team.
  • Work with lead researchers on study design and the preparation of sample size and power calculations. Provide the lead researcher with final data tables, figures, and listings and interpretation of the results.
  • Perform bioinformatics analysis of next generation sequencing datasets including transcriptomic and genomic data
  • Develop and present research for meetings or conferences as well as write statistical method sections for manuscripts and grant applications.
  • Perform data management, statistical tasks or other duties as assigned.

Education and Experience
  • Position requires a minimum of a Doctoral degree in biostatistics or related field and no relevant experience, or a Master's degree in biostatistics or related field and 2 years relevant experience, or a Bachelor's degree in biostatistics or related field and 4 years relevant experience.
  • Experience with R and SAS programming.
  • Experience with UNIX/Linux environment.
  • Experience with Python, Perl, C++ or equivalent programming languages.
  • Experience with bioinformatics, assay analysis, development and assessment.
  • Good written and oral communication skills.

Working at DHVI
  • The DHVI environment offers a unique collaborative opportunity in scientific community.
  • Competitive salary and excellent benefits from Duke University.
  • Collaboration with highly motivated, world class colleagues from around the world.
  • The chance to participate in research at the highest level.
  • Exposure to many leaders in the field in genomics, bioinformatics, virology, and immunology.


Requisition Number
401396944

Location
Durham

Duke Entity
MEDICAL CENTER

Job Code
2682 BIOSTATISTICIAN III

Job Family Level
74

Exempt/Non-Exempt
Exempt

Full Time / Part Time
FULL TIME

Regular / Temporary
Regular

Shift
First/Day

Minimum Qualifications
Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex,sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation,creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions:Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Education

Position requires a minimum of a Doctoral degree in (bio) statistics or related field and no relevant experience, or a Master's degree in (bio)statistics or related field and 2 years relevant experience, or a Bachelor's degree in (bio) statistics or related field and 4 years relevant experience.

Experience

OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE Contribution to analysis of clinical trials and/or clinical research projects, and/or participation in preparation of academic manuscripts or other written summaries of analysis results, thorough experience with SAS, and solid command of the English language is required. Desirable experience includes prior role as a lead statistician on clinical trials and/or clinical research projects that have delivered the agreed-upon end products on time, and prior guidance of lower level or less experienced staff.

Auto req ID

98744BR

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, genetic information, gender, gender expression, gender identity, national origin, race, religion, sexual orientation, or veteran status.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

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Job No:
Posted: 3/22/2018
Application Due: 5/21/2018
Work Type:
Salary: