Life Science Research Professional 2
Life Science Research Professional 2
Job Number: 78087
The Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine is currently recruiting a Life Science Research Professional 2 to join Dr. Sergiu Pasca's laboratory. The Pasca laboratory explores the biological mechanisms of brain disease using cellular models of the human brain generated using reprogramming technology (iPS cells). The laboratory has developed novel technology that allows to take stem cells from healthy people and patients and engineer self-assembling 3D structures called brain region-specific spheroids or organoids (Nature Methods 2015; Neuron; 2017). These 3D brain tissue resembles specific regions of the nervous system and can be assembled to study the cross-talk between cells in the human brain (Nature 2017). The ultimate goal of the lab is to identify novel and reliable drug targets for neuropsychiatric disorders.
The candidate for this position should have experience with human stem cells, genome engineering in human cells (CRISPR/Cas9) and/or neural differentiation, and will contribute to exciting projects in the lab aimed at understanding how specific genes associated with autism and other neurodevelopmental conditions lead to disease.
For more information on the Pasca lab and research being performed please visit their website at www.pascalab.org.
- Perform complex (lab and/or field) experiments for a major portion of the research project. Maintain detailed records of experiments and outcomes.
- Interpret and analyze results, often where few guidelines exist. Based on prior results, contribute to development of new research protocols and procedures or adaptation of existing protocols.
- Make recommendations on plan design and/or research direction to principal investigator.
- Work with health and safety department to ensure lab complies with regulations and all required trainings.
- Participate in multidisciplinary teams across different faculties or schools.
- Oversee supply and equipment budget under supervision of principal investigator or business manager.
- Perform ongoing literature review to remain current with new procedures and related research; present findings for lab work group.
- Contribute substantively to the preparation of papers for publication, especially in the results section. May contribute to publication of findings and present ongoing work and findings to colleagues at academic conferences.
- Supervise (either formally or informally) staff or students as needed, including oversight and instruction on techniques, as well as consultation on project work. Serve as technical resource for other research staff.
- Perform general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed. May assist with purchasing laboratory equipment.
- Doctoral degree
- Knowledge and experience with stem cell biology, molecular and cell biology techniques including CRISPR/Cas9 genome editing and neural differentiation
Bachelor's degree in related scientific field and three years of related experience, or Master's degree.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- Comprehensive understanding of scientific principles.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Strong analytical skills and excellent judgment.
- Ability to work under deadlines with general guidance is essential.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.
Location: School of Medicine
To be considered for this position please visit our web site and apply on line at the following link: stanfordcareers.stanford.edu
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.