Laboratory Specialist Intermediate

Charlottesville, VA
Feb 28, 2018
Institution Type
Four-Year Institution

Working Title: Laboratory Specialist Intermediate

Position Type: University Managerial and Professional Staff

Department: Center for Public Health Genomics

Location: Charlottesville

Posting Date: 12-07-2017

Posting Summary:
The Miller Laboratory at the University of Virginia seeks a highly motivated Laboratory Specialist Intermediate with a background in the life sciences (e.g. genetics, molecular biology, cell biology, developmental biology, engineering or similar fields) to investigate the genetic basis of coronary artery disease. Our group investigates the causal mechanisms of loci associated with coronary artery disease and related cardiovascular diseases, with a focus on understanding the regulation and targeting of mural cell signaling pathways. These efforts are expected to reveal the 'hidden risk' for complex diseases for more precise prediction and early stage prevention.

The candidate will be involved in generating various bulk and single-cell genomic datasets (e.g. RNA-seq, ATAC-seq, ChIP-seq) from both normal and diseased environments, in order to study mural cell regulation and disease mechanisms. In addition, the candidate will serve as a laboratory manager and will thus be responsible for maintaining day-to-day lab operations, including ordering, laboratory safety, IRB, and animal protocols. The candidate will be expected to perform routine histology/immunohistochemistry, tissue dissection, and cell culture. The candidate will be expected to work independently on protocol optimization, data collection and analysis and will be expected to assist in training lab members as needed. The candidate will benefit from a highly interactive environment in the Center for Public Health Genomics, with strong collaborations with nearby labs and members of the Robert M. Berne Cardiovascular Research Center.

Candidates must have a Bachelor's degree in the life sciences or a related field by appointment start date, with a minimum of five years of research experience. A Master's degree in a related field may substitute for this required experience. Experience in human genetics, molecular biology, engineering or similar field is preferred. Excellent written and oral communication skills is required, as is excellent organization and management skills. Knowledge of genome editing, high-throughput screens, or next generation sequencing is preferred.

For additional information about the position and application process, please contact Dr. Clint L. Miller (clintm at

This is a restricted position contingent upon the continuation of funding.

Required Knowledge, Skills and Abilities:
Excellent written and oral communication skills is required, as is excellent organization and management skills.

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