RESEARCH TECHNICIAN II

Location
Durham, NC
Posted
Feb 28, 2018
Institution Type
Four-Year Institution

diversity employer



RESEARCH TECHNICIAN II
Molecular Genetics and Microbiology

This position is for approximately one year with extensions contingent on funding and performance.

Occ Summary

Perform a variety of complex technical duties involved in conducting laboratory tests, experiments
and determinations in support of the investigation of the molecular biology of Cerebral Cavernous
Malformations, an inherited cerebrovascular disease. Using genetically engineered mouse model of
the disease, the lab visually traces the lineage of mutant endothelial cells, investigate novel drug
therapies, and analyze tissue from micro dissected CCM tissue for somatic mutations.

Must have:
Experience handling mice
Knowledge of mouse genetics

Strong Preference:
Familiarity with DNA sequencing
Familiarity with analysis of DNA sequence

Skills/techniques that would be useful to already have:
Minimal programming skills for DNA sequence analysis
Fluorescence microscopy experience
Histology experience

Work Performed

Perform a variety of complex technical duties involved in conducting physical, chemical, biological
and other research laboratory tests, experiments and determinations to obtain data for research
purposes; compile, analyze, document and draw tentative conclusions from experimental results.

Animal husbandry (including setting up matings, weaning, and maintaining lines), animal injections, examination of organs/tissues (both gross and microscopic).

Confer with principal investigator/lab manager/Postdocs to review work assignments and develop
plans for research experiments; make minor modifications to existing laboratory procedures and techniques
to meet the needs of the particular equipment as required.

Review laboratory methods manual, scientific journals, abstracts and other literature for
information applicable to research experiments.

Determine and set up instruments, material and apparatus and operate laboratory equipment required
for specific tests.

Obtain, prepare, mount and stain tissue, blood and other substances for microscopic examination.

Prepare culture media, chemicals, reagents and solutions.

Maintain sufficient inventory of material, supplies and equipment for performance of duties; clean
and maintain laboratory equipment.

Review work of lower level laboratory personnel within designated areas and assist in training new
personnel as appropriate.

Perform other related duties incidental to the work described herein.

The above statements describe the general nature and level of work being performed by individuals
assigned to this classification. This is not intended to be an exhaustive list of all responsibilities and duties required of personnel so classified.

Knowledge, Skills and Abilities
The Successful candidate must have excellent technical, record keeping, and communication (written
and verbal) skills. Ability to work under supervision, as part of a team, and independently at times

Requisition Number
401382246

Location
Durham

Duke Entity
MEDICAL CENTER

Job Code
951 RESEARCH TECHNICIAN II

Job Family Level
08

Exempt/Non-Exempt
Non-exempt

Full Time / Part Time
FULL TIME

Regular / Temporary
Regular

Shift
First/Day

Minimum Qualifications
Duke University is an Affirmative Action/Equal Opportunity Employercommitted to providing employment opportunity without regard to anindividual's age, color, disability, gender, gender expression, genderidentity, genetic information, national origin, race, religion, sex,sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation,creativity, and belonging. Our collective success depends on the robustexchange of ideas—an exchange that is best when the rich diversity ofour perspectives, backgrounds, and experiences flourishes. To achievethis exchange, it is essential that all members of the community feelsecure and welcome, that the contributions of all individuals arerespected, and that all voices are heard. All members of our communityhave a responsibility to uphold these values.
Essential Physical Job Functions:Certain jobs at Duke University and Duke University Health System mayinclude essential job functions that require specific physical and/ormental abilities. Additional information and provision for requests forreasonable accommodation will be provided by each hiring department.

Education

Work requires a bachelor's degree in botany, biology, zoology or otherscience related scientific field.

Experience

None required above education/training requirement.OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE

Auto req ID

97635BR

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, genetic information, gender, gender expression, gender identity, national origin, race, religion, sexual orientation, or veteran status.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

PI101381464

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