Senior Bioinformatician

Chicago, IL
Feb 21, 2018
Institution Type
Four-Year Institution

Hyde Park Campus

2010011 BSD - Center for Research Informatics

About the Unit
The Center for Research Informatics (CRI) provides the University of Chicago Biological Sciences Division (BSD) with informatics resources, services, and expertise to enable world-class research. The CRI offers state-of-the-art technologies for working with research data, from data acquisition and storage to analysis and sharing. Our resources are secure, standards-compliant, and open to all members of the BSD. We collaborate with scientists through all stages of their projects, handling clinical, translational, and basic science data with the highest level of efficiency and security. The Bioinformatics core at the CRI is dedicated to providing Bioinformatics analysis support, consulting services, training and grant writing assistance fully developing the bioinformatics components of grant applications. Members of the Bioinformatics core perform as research partners and collaborators, to conceive, plan, design, implement, deploy, operate, and support biomedical research. The CRI is looking for individuals who will contribute their skills in a fast-paced cutting-edge environment and will be leveraging state-of-the-art technologies to deliver innovative and exciting Bioinformatics solutions for researchers.

Job Information

Job Summary:

As a Senior Bioinformatician, you will use strong scientific knowledge and programming skills to design and implement bioinformatics services for research projects at the Biological Sciences Division. You will be focused on hands-on technical activities for a wide range of high-throughput genomics technologies, including the applications of Next Generation Sequencing, spanning pipeline development, optimization, operations, and support.

  • Developing and implementing methodologies and tools as needed, keeping abreast of industry trends and new technologies, and recommending potential solutions based on the latest technical developments. You will use the community best practices, to prototype, develop, execute, test and roll out production level Bioinformatics analysis pipelines.
  • Analyze data of high complexity by applying sound statistical and commonly accepted bioinformatics methods on collaborative projects.
  • Lead projects as the primary bioinformatics resource to ensure they are managed in a timely and efficient manner, appropriately documented, and provide follow up support services after initial project completion.
  • Revise or modify procedures to solve complex problems and work at a high technical level in all phases of data management and bioinformatics support activities.
  • Work on a team of Bioinformaticians, and frequently interact with the BSD Faculty. You will also engage with the bioinformatics community at large on pipeline development and have opportunities to collaborate with internationally recognized leaders in genomics and biomedical informatics.
  • Participate in the writing and delivery of presentations; grant proposal sections, and manuscript sections.

  • Basic knowledge of molecular biology
  • Basic knowledge of statistics
  • Advanced knowledge in bioinformatics
  • Ability to train others
  • Knowledge of regulatory policies and procedures
  • Analytical skills
  • Problem-solving skills
  • Attention to detail
  • Organizational skills
  • Excellent verbal and written communication skills
  • Ability to work independently and as part of a team
  • Knowledge of HIPAA policies preferred

Additional Requirements

  • Doctoral degree in Bioinformatics, the Biological Sciences, Computer Science, or a related field required.

  • Two (2) or more years of experience in the field of bioinformatics
  • Two (2) or more years of experience programming in at least three (3) of the following languages: Python, Java, SQL, XML, Perl, and R
  • Demonstrated experience and proficiency in analysis pipeline development of high- throughput data
  • Hands-on experience with next generation sequencing technologies such as BWA, Novoalign, STAR, GATK, samtools, Picard, and other tools
  • Experience and a working understanding of algorithms, data structures, and scientific programming
  • Experience working on Linux and/or Unix systems
  • Experience working on High Performance Computing (HPC) infrastructure
  • Demonstrated experience in the development, optimization, automation, and operations support of analysis pipelines for high-dimensional data including whole-genome, whole- exome, and RNA sequencing data preferred
  • Experience in employing high performance computing to solve parallelizable compute problems preferred
  • Experience providing bioinformatics services or other service roles preferred.
  • Experience with project management preferred
  • Experience with genomic datasets such as TCGA, TARGET, CGCI, MMRF, and ICGC preferred
  • Experience with version control, such as git, preferred
  • Experience with both molecular and clinical data preferred
  • Experience mentoring early career bioinformaticians preferred

Required Documents:
  • Cover Letter
  • Resume
  • Writing sample (preferred)
  • Research Statement (preferred)

Benefit Eligibility

Pay Frequency

Pay Range
Depends on Qualification

Scheduled Weekly Hours


Job is Exempt?

Drug Test Required?

Does this position require incumbent to operate a vehicle on the job?

Health Screen Required?

Background Check Required?


Posting Date

Remove from Posting On or Before

Posting Statement:

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Full time

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