Research Specialist 2 - Keenan

Job description

Hyde Park Campus

20146 Biochem/Mol Bio

About the Unit
The Department of Biochemistry & Molecular Biology (BMB) studies how biomolecules operate and interact to drive the complex and diverse behaviors of living systems. The questions that we ask are broad and multifaceted, and as a result, our trainees are well equipped for future academic and industrial careers in biochemistry and biophysics. Our research encompasses all areas of modern biochemistry, including structural biology, biophysics, and biomolecular engineering and design. Our Department is distinguished by its intellectual rigor and collaborative style. Interdisciplinary interactions are further facilitated by our presence in the Gordon Center for Integrative Sciences, which brings together a large and diverse group of biological and physical scientists to pursue common research goals.

Job Information

Job Summary:

We seek a highly motivated and experienced researcher who will manage laboratory operations and perform complex, collaborative research on the molecular basis of membrane protein biogenesis. They will carry out a variety of computational, structural, biochemical and cellular experiments, develop new methods, independently maintain collaborations, train and supervise undergraduates and/or rotation students, and provide assistance and training to graduate students and postdoctoral fellows working on related projects. They will have responsibility for the day-to-day operations of a high-performing research laboratory with purchasing authority and accountability for safe, efficient laboratory operations.



  • Independently carry out complex research projects
  • Build computational pipeline for analysis of large cryo-electron microscopy datasets
  • Clone, mutate, tag, express, purify, and interrogate the behavior of proteins and protein complexes in vitro and in cells
  • Clone, mutate, tag, express, purify, and interrogate the behavior of proteins and protein complexes in vitro and in cells.
  • Execute collaborative research projects with minimal supervision
  • Prepare recombinant DNA constructs and expressing and purifying proteins from human cells, insect cells, Saccharomyces cerevisiae and Escherichia coli
  • Carry out structural, and biochemical measurements on proteins and complexes
  • Build and leverage a computational pipeline for structural studies by cryo-E

  • Manage and maintain a computational pipeline for structural analysis
  • Maintain laboratory and its members in compliance with health and safety regulations and training
  • Maintain a safe and organized laboratory
  • Acquire materials needed for research group, including negotiate purchasing agreements
  • Professionally maintain collaborative relationships with multiple research organizations
  • Respond to materials requests
  • Train graduate and undergraduate students

  • Ability to train others required
  • Knowledge in relevant scientific field required
  • Knowledge of research techniques or methods required
  • Knowledge of regulatory policies and procedures required
  • Knowledge of safety standards, policies, and procedures required
  • Analytical skills required
  • Problem-solving skills required
  • Attention to detail required
  • Organizational skills required
  • Verbal and written communication skills required
  • Ability to work independently and as part of a team required
  • Ability to guide team members without direct authority required
  • Ability to develop vendor relationships and negotiate favorable purchasing agreements required
  • Knowledge of Microsoft Office required
  • Ability to read and keep abreast of technical developments required
  • Ability to handle multiple tasks under performance and time-related stress required
  • Knowledge of data analysis preferred
  • Publication record preferred

Additional Requirements

Education, Experience and Certifications:

  • Bachelor's degree or higher in a field relevant to this research being conducted required

  • Knowledge and basic skills in data programs required
  • Experience in computational biology required
  • Experience in UNIX, R programming required
  • Experience in structural and molecular required
  • Supervisory experience requied
  • Preferred: Experience with computer programs, standard molecular and biochemistry laboratory equipment

Working Conditions and Physical Requirements:
  • Ability to sit for up to two hours
  • Ability to use computers extensively for two to fours hours
  • Ability to stand for four hours or more
  • Laboratory environment

Required Documents:
  • Resume
  • Reference Contact Information

Benefit Eligibility

Pay Frequency

Pay Range
Depends on Qualification

Scheduled Weekly Hours


Job is Exempt?

Drug Test Required?

Does this position require incumbent to operate a vehicle on the job?

Health Screen Required?

Background Check Required?


Posting Date

Remove from Posting On or Before

Posting Statement:

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

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Full time

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Job No:
Posted: 2/21/2018
Application Due: 4/22/2018
Work Type: