Research Specialist I/II

Job description

Requisition # 2018-8386
Department Princeton Neuroscience Inst
Category Research and Laboratory
Full-Time / Part-Time Full-Time
Application Deadline


Research Specialist I/II

The lab of Prof. Sebastian Seung in the Princeton Neuroscience Institute at Princeton University is seeking a full-time Research Specialist. The specialist will apply cutting-edge neuroanatomical techniques for observing brain structure. The techniques may be experimental, such as electron microscopy, whole-brain light microscopy, viral labeling, and immunolabeling. An example of a recent publication can be found here.


  • Undertake projects or tasks related to electron microscopy.
  • Undertake EM sample preparation and visualization including fixation, embedding and ultrathin sectioning, Immunogold labeling, and negative staining.
  • Ultra-thin sample sectioning and section collection (both manual and automated using ATUMtome)
  • Image acquisition for staining quality assessment using microCT, Scanning Electron Microscopes and Transmission Electron Microscopes
  • Maintain a current understanding of "state-of-the-art" knowledge in EM fields, including correlative light and electron microscopy approaches.
  • Provide training on sample preparation and on the operation of the electron microscopes to other lab members such as postdocs or PhD students.
  • Assist other lab members in specimen preparation, imaging, analysis and documentation.
  • Provide necessary quality-controlled protocols and reagents for direct use in applications or for user applications as needed.
  • Manage laboratory functions such as equipment maintenance, organization, safety, ordering, and preparation of all material and reagent use, chemical stocks and other inventories and training of new personnel on equipment and technical laboratory procedures.


  • A Bachelor's degree in Neuroscience or related discipline.
  • Expertise in biological sample preparation for transmission and scanning electron microscopy.
  • Hands-on knowledge of confocal and wide field fluorescence microscopy is preferred but not necessary.
  • The candidate will help users design innovative experiments and carry out rodent surgeries, sample preparation and imaging as well as assist in data analysis and interpretation.
  • Excellent communication skills, ability to organize a wet lab with multiple users in a supporting role.

The ideal candidate should have the ability to maintain professional standards; demonstrate the ability to work independently and pro-actively with limited supervision, take initiative, creative ability to solve problems and self-directed learner with strong experimental methodological abilities.

  • Electron microscopy
  • Light microscopy
  • Viral labeling
  • Immunolabeling
  • Stereotaxic surgery
  • Image analysis software and systems (e.g. FIJI/ImageJ, EyeWire)

The position will begin immediately. Applications should include a CV and list of three references. Review of applications will continue until the position is filled. This is a one-year term position with the possibility of extension contingent upon satisfactory performance and continued funding.

Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. EEO IS THE LAW

Salary Grade

RSP, 020

Standard Weekly Hours


Eligible for Overtime


Benefits Eligible


Essential Services Personnel (see policy for detail)


Estimated Appointment End Date


Physical Capacity Exam Required


Valid Driver's License Required


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Job No:
Posted: 1/19/2018
Application Due: 3/20/2018
Work Type: