Dec 16, 2017
Institution Type
Four-Year Institution

Duties: The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the 'go-to' organization for public and private partners, who want to participate in the gene therapy space. Currently we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

We are currently looking Research Specialist C, to support research efforts in induced pluripotent stem cells (iPSCs) and disease modeling.

As a Research Specialist C, you will collaboratively plan and independently perform stem cell culture activities. You will be trained by Senior Research Investigator on in vitro and in vivo disease modeling. experiments under the management of a supervising scientist. You will also aid other scientists in their research by performing biochemistry and molecular biology assays such as plasmid cloning and manipulation, PCR, western blot, and ELISA; cell biology assays such as flow cytometry, function assay of differentiated cells; animal manipulation such as xenograft, perfusion, and necropsy. You will be expected to keep abreast of the work of scientists within GTP, external research being conducted in the same field, and you will help in the preparations of presentations and writing of original manuscripts.

The experiments performed in this team will require individuals to work rotating weekends as part of their regular schedule.

Qualifications: B.A./B.S. in Biology, Molecular Biology, Cell Biology, Biochemistry, Chemistry or in adjacent field with strong scientific background and 3-5 years of post-degree bench laboratory experience, or an equivalent combination of education and experience required
Experience with mammalian cell/tissue culture required; stem cell culture preferred
Experience with Molecular Biology and Biochemistry techniques/assays (cloning, isolations, PCR, ELISA, animal/colony handling/maintenance, genotyping, and dissection) strongly preferred.
Must be willing to learn new techniques involving molecular and cell biology, protein biochemistry, virology, immunology, bioinformatics, and biotechnology.
Must have the ability to follow existing and ability to develop novel protocols and methods; Outstanding interpersonal interaction skills, excellent written and oral communication skills, problem recognition and solving, and organizational skills required
Must be able to work rotating weekends and holidays.

Reference Number: 40-27601

Salary Grade: 026

Employment Type: Exempt

Org: DM-Gene Therapy Program

Special Requirements:

Job Family: I-Technical/Professional Research

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