Job description

Duties: The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the 'go-to' organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

Due to expansion, GTP is looking for a new Director of Research - Cancer(DRC) to lead gene therapy translational research projects as well as contribute to the strategic growth of GTP and our Cancer gene therapy pipeline.

As the DRC, in consultation with PI of Gene Therapy Program, you will assess the rare disease programs that are brought into GTP for scientific research. You will identify and develop new therapeutic programs in gene therapy for cancer research, establishing project plans, protocols, and project resourcing. You will design, optimize and implement complex experiments; develop and optimize novel therapeutics in animal disease models. You will establish processes for mentoring & leading Senior Research Investigators(SRI) in cancer research projects so that they can function independently within GTP when using standard tools, directly oversee and manage a team of SRIs and technicians. You will promote investigator directed activities through presentations at key scientific meetings, emerging as an academic leader in gene therapy related to cancer research as evidenced by seminars at national meetings and peer-reviewed papers in scholarly journals. You will develop and maintain relationships with key internal and external opinion leaders and investigators, companies, academic laboratories and primary customers regarding advances in the field, collaborative studies, and product-related issues and needs. You will manage preparation and submission of high-quality regulatory dossiers in the US, EU, and Japan requiring cross-functional interactions, excellent project management, and writing skills, as well as a good understanding of the underlying science.

You should have in-vivo pharmacology expertise for pre-clinical translational programs as well as expertise in testing the efficacy of therapeutic interventions for cancer disease models. Research experience in CNS malignancy models would be helpful.

Qualifications: * A Master's degree in Biology, Virology, Immunology, or related major and 5-7 of translational research experience, or an equivalent combination of education and experience, are required.
* Ph. D. strongly preferred
* Extensive experience working with animal models required
* Research experience in CNS malignancy models strongly preferred
* Industry experience helpful but not required
* Must be a self starter but also have a strong desire to contribute and work collaboratively to achieve goals
* Must have a track record of success in roles requiring execution of multiple tasks while responding to multiple priorities
* Must be highly functioning, detail-oriented, and analytical candidate who can think strategically
* Excellent oral/written communication skills required

Reference Number: 40-27136

Salary Grade: 030

Employment Type: Exempt

Org: DM-Gene Therapy Program

Special Requirements:

Job Family: B-Executive/Managerial Administration




Diversity Profile: University



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Job No:
Posted: 10/21/2017
Application Due: 10/21/2018
Work Type: