Research Associate

Charlottesville, VA
Oct 03, 2017
Institution Type
Four-Year Institution

Working Title: Research Associate

Position Type: Professional Research Staff

Department: Beirne B. Carter Center for Immunology Research

Location: Charlottesville

Posting Date: 08-11-2017

Posting Summary:
The Beirne B. Carter Center for Immunology Research at the University of Virginia seeks a postdoctoral Research Associate to study immune mechanisms of virus control in Michael Brown's laboratory. This project will investigate how NK cells mediate virus control and protection of lymphoid architecture in the mouse spleen during murine cytomegalovirus (MCMV) infection. Previous work uncovered several quantitative trait loci (QTL) that affect the capacity of NK cells to mediate viral clearance and tissue protective effects, but the basis for regulation of these critical NK functions remains unknown (Gillespie et al (2016) PLoS Pathogens 12(2): e1005419). Classical genetics with genetic screening and genome editing, cellular immunology, bone marrow transplantation, immune cell adoptive transfer and molecular biological approaches will be implemented to precisely map, identify and characterize critical genetic modifiers of NK cells. A major goal is to understand how diversity in NK receptors and their ligands, and additional genetic modifiers together shape NK cell functionality, NK impacts on other immune cells, and inflammatory responses during viral infection, which can serve to model genetic effects known to influence clinical outcomes in human patients suffering from chronic viral infection.

The Beirne Carter Center offers a collaborative immunology community and work environment with outstanding research facilities.

Candidates must have an M.D. and/or a Ph.D. degree in Immunology in hand by the start date and additional experience in Biochemistry, Genetics, Microbiology, or Molecular Biology. The individual should be self-motivated and have developed skills in mentoring, written and oral communication, and the design and analysis of experimental questions.

To apply visit and search for Posting Number 0620471. Applicants should complete a candidate profile, and attach a cover letter, CV, statement of research interest, and a list of three references. For questions regarding the position or application process, please contact Michelle Butler at

This position is restricted and contingent upon the continuation of funding. The position will remain open until filled.

The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.

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