Post Doctoral Fellow

Location
Aurora, CO
Posted
Sep 29, 2017
Institution Type
Four-Year Institution




University of Colorado - School of Medicine

Post Doctoral Fellow

A Post-Doctoral Position in Structural Biology is available in the laboratory of Dr David Jones in the Department of Pharmacology to investigate novel drug interaction with the Ras effector proteins Ral A and B. The person will be responsible for performing structural and biophysical studies using X-ray crystallography and biophysical methods to identify and characterize the interaction of novel candidate ligands with the Ral proteins. The ideal candidate will have proven experience in using X-ray crystallography and biophysical analysis for the study of protein structure and function. A strong background in molecular biology and protein chemistry techniques to prepare proteins for structural studies is also required. While not essential, experience or a willingness to learn NMR spectroscopy methods is also desired

Skills Required

  • Experience in X-ray crystallography is required
  • Experience in Biophysical analysis of protein-ligand interactions, including fluorescence spectroscopy, CD spectroscopy, calorimetry
  • Basic Molecular Biology and microbiology techniques for cloning and expression of proteins.
  • Experience in liquid chromatography techniques applied to protein purification.


Supervision and Training

This position may train graduate students, undergraduate students, and postdoctoral fellows

Qualifications

Minimum Qualifications:

  • Graduation from an accredited college or university with a Ph.D.
  • Minimum of 3 years laboratory experience
  • Excellent communication and organizational skills
  • The ability to work independently within the research lab on your own research project
  • Computer software knowledge and laboratory technical skills and experience commensurate with experience


Desired or preferred




Experience with NMR spectroscopy or X-ray crystallography

Special conditions of employment

Must be eligible to work in the US or eligible to apply for a work visa through the University


Application Materials Required:Cover Letter, Resume/CV, List of References

Application Materials Instructions:

Applications are accepted electronically at CU Careers, refer to requisition ID: 11225

When applying, applicants must include:
  1. A letter of application which specifically addresses the job requirements and outlines qualifications
  2. A current Resume/CV
  3. The names, addresses, daytime telephone numbers and e-mail addresses for three professional references, either attached to your resume/CV or uploaded as a separate document
Please be advised that the University does check references as part of the employment process.

Please do not submit any of your application material (via email) to the job posting contact.



Job Category: Faculty

Primary Location: Aurora

Department: H0001 -- Anschutz Medical Campus - 20120 - SOM - Pharmacology

Schedule: Full-time

Posting Date: Sep 25, 2017

Closing Date: Ongoing

Posting Contact Name: Jennifer Orsund

Posting Contact Email: jennifer.orsund@ucdenver.edu

Position Number: 00633517

PI99605883