Position Type: Permanent Staff
Department: Lineberger Compr Cancer Center - 426801
Appointment Type: EHRA Non-Faculty Research
Vacancy ID: NF0002699
Position Summary: Lineberger Comprehensive Cancer Center lab focuses on implementing therapeutic RNA-interference (RNAi) with nanoparticles to target metastatic biology in lung cancer. We are actively pursuing several leads that are responsible for metastasis, and we are especially interested in the role of manipulating the tumor microenvironment. Our overall goal is to study mechanisms of lung cancer metastasis and translate novel RNAi therapeutics into the clinic. This position will design, manage and execute experiments in accordance with the lab's focus. This will include optimizing assays, potential screening efforts, screen validation and follow-up studies. Assist with manuscript and grant writing. Will work collaboratively with other researchers in the lab and within Lineberger.
Education Requirements: BA or BS in biological sciences and 3 years laboratory experience required. Masters or PhD preferred.
Qualification and Experience: At least 3 years biochemical and molecular biology experience is required. Experience with mammalian tissue culture is required. Experience with reporter assays and sub-cloning expertise is desired. Experience using Adobe Photoshop and Illustrator are preferred. Transfection of cultured human cells with DNA, miRNA and siRNA, generation and handling of retro- and lenti-viruses for delivery into human tissue culture cells, protein immune-precipitation, experience with flow cytometry or FACS (fluorescence activated cell sorting) and fluorescence microscopy are preferred.
Equal Opportunity Employer: The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or status as a protected veteran.
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